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cypress leaf oil

General Material Information

Preferred name cypress leaf oil
Trivial Name Cypress oil
Short Description volatile oil obtained from the leaves of the cypress, cupressus sempervirens l., pinaceae
CAS Number 8013-86-3
FDA UNII Search
Synonyms
  • cupressus pyramidalis leaf oil
  • cupressus sempervirens leaf oil
  • cupressus sempervirens var. stricta leaf oil
  • cypress (spain) ess. oil (for fragrance) (Robertet)
  • cypress EO
  • cypress essential oil
  • cypress leaf oil (cupressus sempervirens)
  • cypress leaf oil morocco
  • cypress leaf oil spain
  • cypress leaves EO
  • cypress oil france / morocco organic
  • cypress oil organic
  • cypress oil, rectified
  • cypress organic oil
  • cypress TICO 13 (Takasago)
  • hydroessential cupressus (Vevy)
  • volatile oil obtained from the leaves of the cypress, cupressus sempervirens l., pinaceae
  • cupressus sempervirens l. leaf oil
  • Cypress oil
  • Oils, cypress
  • Oil of Cypress
  • Cypress oils

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Literature & References

cupressus sempervirens l. leaf oil
Canada Domestic Sub. List:8013-86-3
Pubchem (sid):135320339
Publications by PubMed
Antiproliferative, Antifungal, and Antibacterial Activities of Endophytic Alternaria Species from Cupressaceae.
Novel merosesquiterpene exerts a potent antitumor activity against breast cancer cells in vitro and in vivo.
Labda-8(17),12,14-trien-19-oic Acid Contained in Fruits of Cupressus sempervirens Suppresses Benign Prostatic Hyperplasia in Rat and In Vitro Human Models Through Inhibition of Androgen and STAT-3 Signaling.
[Cypress pollen allergy].
In-vitro Antimicrobial Activities of Some Iranian Conifers.
Molecular detection assay of the bud mite Trisetacus juniperinus on Cupressus sempervirens in nurseries of central Italy.
Essential-oil composition of the Tunisian endemic cypress (Cupressus sempervirens L. var. numidica TRAB.).
Flammability of some ornamental species in wildland-urban interfaces in southeastern France: laboratory assessment at particle level.
Description of a new relict eriophyoid mite, Loboquintus subsquamatus n. gen. & n. sp. (Eriophyoidea, Phytoptidae, Pentasetacini) based on confocal microscopy, SEM, COI barcoding and novel CLSM anatomy of internal genitalia.
Relevance of the Sea Sand Disruption Method (SSDM) for the biometrical differentiation of the essential-oil composition from conifers.
The skin prick test - European standards.
Extraction of essential oil from Cupressus sempervirens: comparison of global yields, chemical composition and antioxidant activity obtained by hydrodistillation and supercritical extraction.
Essential oil composition, adult repellency and larvicidal activity of eight Cupressaceae species from Greece against Aedes albopictus (Diptera: Culicidae).
Chemical analysis and biological activities of Cupressus sempervirens var. horizontalis essential oils.
Leaf plasticity to light intensity in Italian cypress (Cupressus sempervirens L.): adaptability of a Mediterranean conifer cultivated in the Alps.
Allergomic study of cypress pollen via combinatorial peptide ligand libraries.
Identification of the plant origin of the botanical biomarkers of Mediterranean type propolis.
Ephedra alte (joint pine): an invasive, problematic weedy species in forestry and fruit tree orchards in Jordan.
The loss of essential oil components induced by the Purge Time in the Pressurized Liquid Extraction (PLE) procedure of Cupressus sempervirens.
In vitro antiplasmodial, antileishmanial and antitrypanosomal activities of selected medicinal plants used in the traditional Arabian Peninsular region.
Differential IgE sensitization to cypress pollen associated to a basic allergen of 14 kDa.
Proteomics of cypress pollen allergens using double and triple one-dimensional electrophoresis.
Arthrobacter cupressi sp. nov., an actinomycete isolated from the rhizosphere soil of Cupressus sempervirens.
Batch and dynamic biosorption of basic dyes from binary solutions by alkaline-treated cypress cone chips.
Structural characterization of the O-chain polysaccharide from an environmentally beneficial bacterium Pseudomonas chlororaphis subsp. aureofaciens strain M71.
Prevalence and real clinical impact of Cupressus sempervirens and Juniperus communis sensitisations in Tuscan "Maremma", Italy.
Linkage mapping of the Mediterranean cypress, Cupressus sempervirens, based on molecular and morphological markers.
Antioxidant and antiacetylcholinesterase activities of some commercial essential oils and their major compounds.
Protective role of Juniperus phoenicea and Cupressus sempervirens against CCl(4).
Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides.
Rhizosphere dynamics during phytoremediation of olive mill wastewater.
Effectiveness of Cupressus sempervirens cones as biosorbent for the removal of basic dyes from aqueous solutions in batch and dynamic modes.
Biodegradable gelatin-chitosan films incorporated with essential oils as antimicrobial agents for fish preservation.
Cypress pollen does not cross-react to plant-derived foods.
Biomonitoring of chemical elements in an urban environment using arboreal and bush plant species.
8,8''-Biapigeninyl stimulates osteoblast functions and inhibits osteoclast and adipocyte functions: Osteoprotective action of 8,8''-biapigeninyl in ovariectomized mice.
Barriopsis iraniana and Phaeobotryon cupressi: two new species of the Botryosphaeriaceae from trees in Iran.
An insight into some relevant aspects concerning eriophyoid mites inhabiting forests, ornamental trees and shrubs.
Molecular evidence for the natural production of homozygous Cupressus sempervirens L. lines by Cupressus dupreziana seed trees.
Constituents from fruits of Cupressus sempervirens.
Molecular and morphological characterization of Dothiorella casuarini sp. nov. and other Botryosphaeriaceae with diplodia-like conidia.
Allergenicity and cross-reactivity of pine pollen.
Evaluation of the in vitro anticancer, antimicrobial and antioxidant activities of some Yemeni plants used in folk medicine.
Is Cupressus sempervirens native in Italy? An answer from genetic and palaeobotanical data.
Genotype-specific regulation of cold-responsive genes in cypress (Cupressus sempervirens L.).
Antiproliferative effects of essential oils and their major constituents in human renal adenocarcinoma and amelanotic melanoma cells.
Selection of woody species for wastewater enhancement and restoration of riparian woodlands.
The Cypress aphids in the South of France.
In vitro antimicrobial activity and antagonistic effect of essential oils from plant species.
Prevalence of cypress pollen sensitization and its clinical importance in Izmir, Turkey, with cypress allergy assessed by nasal provocation.
Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species.
Phytochemical investigation and hepatoprotective activity of Cupressus sempervirens L. leaves growing in Egypt.
Anticoagulant effect of Cupressus sempervirens.
Growth and survival response of potted Cupressus sempervirens seedlings to different soils.
Safety and efficacy of Juniperus ashei sublingual-swallow ultra-rush pollen immunotherapy in cypress rhinoconjunctivitis. A double-blind, placebo-controlled study.
Identification of italian cypress (Cupressus sempervirens) pollen allergen Cup s 3 using homology and cross-reactivity.
Mechanical stability of trees under dynamic loads.
Ritual plants of Muslim graveyards in northern Israel.
Occupational respiratory allergy to cyclamen pollen: a case report.
Chemical and biological characterisation of sapinopyridione, a phytotoxic 3,3,6-trisubstituted-2,4-pyridione produced by Sphaeropsis sapinea, a toxigenic pathogen of native and exotic conifers, and its derivatives.
Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity.
Photoinhibition of photosynthesis in needles of two cypress (Cupressus sempervirens) clones.
Efficacy of sublingual coseasonal immunotherapy with a monomeric allergoid in Cupressaceae pollen allergy--preliminary data.
In vitro antimycotic activity of some plant extracts towards yeast and yeast-like strains.
Allergy to cypress pollen.
Quantification assay for the major allergen of Cupressus sempervirens pollen, Cup s 1, by sandwich ELISA.
Use of pruning waste compost as a component in soilless growing media.
Asthma induced by canary food mix.
An epidemiological survey of Cupressaceae pollenosis in Italy.
Effects of Cupressus sempervirens cone extract on lipid parameters in Wistar rats.
Susceptibility of cypress seedlings to the eriophyoid mite Trisetacus juniperinus.
Damping-off in conifer seedling nurseries in Noshahr and Kelardasht.
Characterization of the developmental stages of cypress zygotic embryos by two-dimensional electrophoresis and by cytochemistry.
Sphaeropsidins D and E, two other pimarane diterpenes, produced in vitro by the plant pathogenic fungus Sphaeropsis sapinea f. sp. cupressi.
Efficacy of sublingual specific immunotherapy in Cupressaceae allergy using an extract of Cupressus arizonica. A double blind study.
Prevalence of sensitization to Cupressus sempervirens: a 4-year retrospective study.
How to reduce air pollution by Cupressus pollen?
[Juniperus ashei: the gold standard of the Cuppressaceae].
[Allergy to cypress pollen: preparation of a reference and standardization extract in vivo].
Environment and sensitization to cypress in Israel.
Efficient transmission of an introduced pathogen via an ancient insect-fungus association
Two-dimensional electrophoretic analysis of proteins associated with somatic embryogenesis development in Cupressus sempervirens L.
Sapinofuranones A and B, two new 2(3H)-dihydrofuranones produced by sphaeropsis sapinea, a common pathogen of conifers
Respiratory allergy to Cupressus sempervirens in Rome.
Double-blind placebo controlled specific immunotherapy with mixed Cupressaceae taxodiaceae pollens in respiratory allergy to Cupressus sempervirens.
Cross-reactivity between Cupressus arizonica and Cupressus sempervirens pollen extracts.
Assessment of skin prick test and serum specific IgE detection in the diagnosis of Cupressaceae pollinosis.
Podocarpus gracilior and Callitris verrucosa--newly identified allergens that crossreact with Cupressus sempervirens.
[The interaction of Cupressus sempervirens L. proanthocyanidolic oligomers with elastase and elastins].
Cypress pollen allergy. Identification of allergens and crossreactivity between divergent species.
Prevalence of patent and latent atopy among a general normal adult population in the south east of France by RAST investigation and correlation with circulating total IgE levels.
Airborne Cupressaceae pollen in southern Italy.
Epitopes on Cry j I and Cry j II for the human IgE antibodies cross-reactive between Cupressus sempervirens and Cryptomeria japonica pollen.
Cypress (Cupressus sempervirens) pollen allergens: identification by protein blotting and improved detection of specific IgE antibodies.
Cross-reactivity between the pollens of Cupressus sempervirens (common cypress) and of Cryptomeria japonica (Japanese cedar).
Increase of respiratory allergy to the pollens of cypresses in the south of France.
[Catechins and flavanolic oligomers from Cupressus sempervirens L. Comparative in vitro elastase inhibitory and in vivo angioprotective activity].
Enzymes of glyoxylate in conifers.
Hay fever due to the pollen of Cupressus sempervirens, Italian or Mediterranean cypress.

Other Information

Export Tariff Code:3301.29.6000
Typical G.C.
Wikipedia:View
FAO:BASIC PRINCIPLES OF STEAM DISTILLATION

PhysChem Properties

Material listed in food chemical codex No
Specific gravity @ 25 °C
Pounds per Gallon 7.239 to 7.414
Refractive Index 1.471 to 1.482 @ 20 °C
Flash Point TCC Value 42.22 °C TCC
Shelf life 12 months (or longer if stored properly.)
Storage notes Store in cool, dry place in tightly sealed containers, protected from heat and light.
Solubility
alcohol Yes
water, 5.358e+004 mg/L @ 25 °C (est) Yes
water No
Stability
bath foam Unspecified
non-discoloring in most media Unspecified
powder Unspecified
soap Unspecified

Organoleptic Properties

Odor Type: Terpenic
fresh, pine, woody, earthy, frankincense, dry, spicy, cedar
Odor strength medium
Substantivity 44 hour(s) at 100.00 %
Luebke, William tgsc, (1987) At 100.00 %. fresh pine woody earthy olibanum dry spicy cedar
Although it originated in Persia, the Cypress plant is also a common sight in Mediterranean landscapes. In Morocco, Cypress is often grown in hedges to protect cropland. The hedges are periodically pruned, providing a raw material that is transformed into an essential oil by Biolandes Maroc. The distillation of Cypress clippings is also a tradition in Provence. A farmer located near our Valréas site has developed certified organic Cypress. The young plants are harvested by machine and yield a very "leafy" raw material. After cutting, they sprout again and regrow. Biolandes' organic (Ecocert EC) essential oil of Cypress is a sustainable product with a significant availability. Terpenic family / aromatic, green, diffusive, spicy
Blends very well with citrus, woody, and aromatic notes, and in masculine fragrances. Has good stability and good odor tenacity. Pine, balsamic, sappy-green wood, rooty
General comment Woody, resinous, peppery, terpenic, sligthly fruity-apple

Occurrences

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 10 - Flammable.
R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Flammable liquids (Category 3), H226
Skin irritation (Category 2), H315
Skin sensitisation (Category 1), H317
Eye irritation (Category 2A), H319
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
Acute aquatic toxicity (Category 1), H400
GHS Label elements, including precautionary statements
Pictogram
Signal word Warning
Hazard statement(s)
H226 - Flammable liquid and vapour
H315 - Causes skin irritation
H317 - May cause an allergic skin reaction
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
H400 - Very toxic to aquatic life
Precautionary statement(s)
P261 - Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 - Avoid release to the environment.
P280 - Wear protective gloves/protective clothing/eye protection/face protection.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
cosmetic and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
alpha-cedrene Max. Found: 0.4 % and Reason: Sensitization
beta-cedrene Max. Found: 0.4 % and Reason: Sensitization
Recommendation for cypress leaf oil usage levels up to:
2.0000 % in the fragrance concentrate.
Recommendation for cypress leaf oil flavor usage levels up to:
not for flavor use.

Safety references

EPI System: View
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8013-86-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
SCCNFP:opinion
WGK Germany:2
cupressus sempervirens l. leaf oil
Chemidplus:0008013863
RTECS:GZ9090000 for cas# 8013-86-3