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trigonella foenum-graecum extract

General Material Information

Preferred name trigonella foenum-graecum extract
Trivial Name Fenugreek extract
Short Description fenugreek extract
CAS Number 84625-40-1
ECHA Number 283-415-1
FDA UNII Search
Synonyms
  • fenugreek extract
  • fenugreek extract natural
  • fenugreek extract WONF natural
  • fenugreek extracts 01
  • fenugreek extracts 02
  • fenugreek fluid extract
  • fenugreek kiinote (Omega)
  • fenugreek spray-dried powder extract
  • trigonella foenum graecum extract
  • trigonella foenum-graecum l. extract
  • Fenugreek, ext.

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Literature & References

trigonella foenum-graecum l. extract
Pubchem (sid):135352329
Publications by PubMed
Antioxidant potential of aqueous extract of some food grain powder in meat model system.
Effect of Trigonella foenum-graecum L. on Metabolic Activity of CYP2D6 and CYP3A4.
The Effects of Fenugreek on Radiation Induced Toxicity for Human Blood T-Cells in Radiotherapy.
Furostanolic saponins from Trigonella foenum-graecum alleviate diet-induced glucose intolerance and hepatic fat accumulation.
Fenugreek Seed Extract Prevents Fat Deposition in Monosodium Glutamate (MSG)-Obese Rats.
Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells.
Pharmacokinetics, tissue distribution and excretion study of a furostanol glycoside-based standardized fenugreek seed extract in rats.
Effect of Centaurium erythraea Rafn, Artemisia herba-alba Asso and Trigonella foenum-graecum L. on liver fat accumulation in C57BL/6J mice with high-fat diet-induced type 2 diabetes.
Trigonella foenum-graceum (Seed) Extract Interferes with Quorum Sensing Regulated Traits and Biofilm Formation in the Strains of Pseudomonas aeruginosa and Aeromonas hydrophila.
Effects of Fenugreek Seed Extract and Swimming Endurance Training on Plasma Glucose and Cardiac Antioxidant Enzymes Activity in Streptozotocin-induced Diabetic Rats.
Influence of a Specialized Trigonella foenum-graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study.
Administration of fenugreek seed extract produces better effects in the glibenclamide-induced inhibition in hepatic lipid peroxidation: An in vitro study.
Characterization of flavonoid glycosides from fenugreek (Trigonella foenum-graecum) crude seeds by HPLC-DAD-ESI/MS analysis.
Hydroalcohol extract of Trigonella foenum-graecum seed attenuates markers of inflammation and oxidative stress while improving exocrine function in diabetic rats.
Antidepressant effect and categorization of inhibitory activity of monoamine oxidase type A and B of ethanolic extract of seeds of Trigonella foenum graecum Linn.
Safety, efficacy and toxicological evaluation of a novel, patented anti-diabetic extract of Trigonella Foenum-Graecum seed extract (Fenfuro).
Effects of fenugreek (Trigonella foenum-graecum L.) seed on bone mechanical properties in rats.
Fenugreek extract diosgenin and pure diosgenin inhibit the hTERT gene expression in A549 lung cancer cell line.
Fenugreek seed extract inhibit fat accumulation and ameliorates dyslipidemia in high fat diet-induced obese rats.
A comparative study on the antioxidant activity of commonly used South asian herbs.
The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads.
The selective cytotoxic anti-cancer properties and proteomic analysis of Trigonella Foenum-Graecum.
Protective effect of Trigonella foenum-graecum on thioacetamide induced hepatotoxicity in rats.
Antioxidant, oxidative DNA damage protective and antimicrobial activities of the plant Trigonella foenum-graecum.
Comparative antioxidant effect of aqueous extracts of curry leaves, fenugreek leaves and butylated hydroxytoluene in raw chicken patties.
Fenugreek induced apoptosis in breast cancer MCF-7 cells mediated independently by fas receptor change.
Variation in chemical composition and allelopathic potential of mixoploid Trigonella foenum-graecum L. with developmental stages.
Catalytic degradation of organic dyes using biosynthesized silver nanoparticles.
[Glycoproteins of mucus of gastric and duodenal wall surface during ulcerogenesis and the impact of fenugreek].
Protective effect of aqueous extract of seed of Psoralea corylifolia (Somraji) and seed of Trigonella foenum-graecum L. (Methi) in streptozotocin-induced diabetic rat: A comparative evaluation.
In vitro α -amylase and α-glucosidase inhibitory potential of Trigonella foenum-graecum leaves extract.
Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek (Trigonella foenum-graecum) seeds and bitter melon (Momordica charantia) fruit.
Protective effect of Trigonella foenum-graecum Linn. on monosodium glutamate-induced dyslipidemia and oxidative stress in rats.
Efficacy and safety of standardized extract of Trigonella foenum-graecum L seeds as an adjuvant to L-Dopa in the management of patients with Parkinson's disease.
A mechanism-based pharmacological evaluation of efficacy of Trigonella foenum graecum (fenugreek) seeds in regulation of dyslipidemia and oxidative stress in hyperlipidemic rats.
Neurobehavioral assessment of hydroalcoholic extract of Trigonella foenum-graecum seeds in rodent models of Parkinson's disease.
Chemomodulatory Effect of Trigonella foenum graecum (L.) Seed Extract on Two Stage Mouse Skin Carcinogenesis.
Antidiabetic Effect of GII Compound Purified from Fenugreek (Trigonella foenum graecum Linn) Seeds in Diabetic Rabbits.
Fenugreek seed extract treats peripheral neuropathy in pyridoxine induced neuropathic mice.
Screening of plants used in Danish folk medicine to treat depression and anxiety for affinity to the serotonin transporter and inhibition of MAO-A.
Characterization and identification of steroidal saponins from the seeds of Trigonella foenum-graecum by ultra high-performance liquid chromatography and hybrid time-of-flight mass spectrometry.
Fenugreek extract as an inducer of cellular death via autophagy in human T lymphoma Jurkat cells.
Antiallergic effect of Trigonella foenum-graecum L. extracts on allergic skin inflammation induced by trimellitic anhydride in BALB/c mice.
Green synthesis of gold nanoparticles using Trigonella foenum-graecum and its size-dependent catalytic activity.
Preventive and curative effect of Trigonella foenum-graecum L. seeds in C57BL/6J models of type 2 diabetes induced by high-fat diet.
Ameliorative effects of standardized extract from Trigonella foenum-graecum L. seeds on painful peripheral neuropathy in rats.
Alkaloid and flavonoid rich fractions of fenugreek seeds (Trigonella foenum-graecum L.) with antinociceptive and anti-inflammatory effects.
Effect of ethanol extract of Trigonella foenum graecum (Fenugreek) seeds on Freund's adjuvant-induced arthritis in albino rats.
The developmental neurobehavioral effects of fenugreek seeds on prenatally exposed mice.
Synthesis and characterization of SIRT6 protein coated magnetic beads: identification of a novel inhibitor of SIRT6 deacetylase from medicinal plant extracts.
Trigonella foenum graecum seed extract protects kidney function and morphology in diabetic rats via its antioxidant activity.
Anaphylactic reactions in mice with Fenugreek allergy.
Physiological aspects of male libido enhanced by standardized Trigonella foenum-graecum extract and mineral formulation.
The Role of Adrenergic and Angiotensinergic Systems in Vascular Effect of Alcoholic of Extract Trigonella foenum-graecum Seed in Diabetic Rats.
Effects of Combined Creatine Plus Fenugreek Extract vs. Creatine Plus Carbohydrate Supplementation on Resistance Training Adaptations.
Anti-hyperglycemic and anti-oxidative effect of aqueous extract of Momordica charantia pulp and Trigonella foenum graecum seed in alloxan-induced diabetic rats.
Anti-hyperglycemic compound (GII) from fenugreek (Trigonella foenum-graecum Linn.) seeds, its purification and effect in diabetes mellitus.
Anti-inflammatory and anti-melanogenic steroidal saponin glycosides from Fenugreek (Trigonella foenum-graecum L.) seeds.
Evaluation of the developmental toxicity of the aqueous extract from Trigonella foenum-graecum (L.) in mice.
In vitro estrogenic activities of fenugreek Trigonella foenum graecum seeds.
Modulation of quorum sensing controlled behaviour of bacteria by growing seedling, seed and seedling extracts of leguminous plants.
New flavonoids with 2BS cell proliferation promoting effect from the seeds of Trigonella foenum-graecum L.
Aqueous extract of Trigonella foenum graecum (fenugreek) prevents cypermethrin-induced hepatotoxicity and nephrotoxicity.
A fenugreek seed extract selectively reduces spontaneous fat intake in overweight subjects.
Complementary and comparative study on hypoglycemic and antihyperglycemic activity of various extracts of Eugenia jambolana seed, Momordica charantia fruits, Gymnema sylvestre, and Trigonella foenum graecum seeds in rats.
Hypolipidemic effect of fenugreek seeds is mediated through inhibition of fat accumulation and upregulation of LDL receptor.
Trigonella foenum-graecum (Fenugreek) protects against selenite-induced oxidative stress in experimental cataractogenesis.
A fenugreek seed extract selectively reduces spontaneous fat consumption in healthy volunteers.
Antioxidant and hepatoprotective activities of Ocimum basilicum Linn. and Trigonella foenum-graecum Linn. against H2O2 and CCL4 induced hepatotoxicity in goat liver.
Rhizobium tibeticum sp. nov., a symbiotic bacterium isolated from Trigonella archiducis-nicolai (Sirj.) Vassilcz.
Acetylcholinesterase enzyme inhibitory potential of standardized extract of Trigonella foenum graecum L and its constituents.
Aqueous and organic extracts of Trigonella foenum-graecum L. inhibit the mycelia growth of fungi.
Fenugreek: a naturally occurring edible spice as an anticancer agent.
Antihyperglycemic effect of Trigonella foenum-graecum (fenugreek) seed extract in alloxan-induced diabetic rats and its use in diabetes mellitus: a brief qualitative phytochemical and acute toxicity test on the extract.
Analgesic and anti-inflammatory activities of Trigonella foenum-graecum (seed) extract.
Studies on Indian green leafy vegetables for their antioxidant activity.
In Vitro Anti-plasmodial activity of Trigonella foenum-graecum L.
Rat growth-hormone release stimulators from fenugreek seeds.
Mechanisms responsible for the vascular effect of aqueous Trigonella foenum-graecum leaf extract in diabetic rats.
Protective action of fenugreek (Trigonella foenum graecum) seed polyphenols against alcohol-induced protein and lipid damage in rat liver.
Differential effects of soybean and fenugreek extracts on the growth of MCF-7 cells.
Glycogen resynthesis and exercise performance with the addition of fenugreek extract (4-hydroxyisoleucine) to post-exercise carbohydrate feeding.
Improved alpha-amylase and Helicobacter pylori inhibition by fenugreek extracts derived via solid-state bioconversion using Rhizopus oligosporus.
In vitro hypoglycemic activity of methanolic extract of some indigenous plants.
Prophylaxis effect of Trigonella foenum graecum L. seeds on renal stone formation in rats.
Fenugreek (Trigonella foenum graecum) seed polyphenols protect liver from alcohol toxicity: a role on hepatic detoxification system and apoptosis.
Fenugreek seed (Trigonella foenum graecum) polyphenols inhibit ethanol-induced collagen and lipid accumulation in rat liver.
Effect of Trigonella foenum-graecum (fenugreek) extract on blood glucose, blood lipid and hemorheological properties in streptozotocin-induced diabetic rats.
Aqueous extract of Trigonella foenum-graecum L. ameliorates additive urotoxicity of buthionine sulfoximine and cyclophosphamide in mice.
Fenugreek (Trigonella foenum graecum) seed extract prevents ethanol-induced toxicity and apoptosis in Chang liver cells.
Biochemical study of the anti-diabetic action of the Egyptian plants fenugreek and balanites.
Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer.
The addition of fenugreek extract (Trigonella foenum-graecum) to glucose feeding increases muscle glycogen resynthesis after exercise.
Spinal serotonergic system is partially involved in antinociception induced by Trigonella foenum-graecum (TFG) leaf extract.
Genotoxicity testing of a fenugreek extract.
Anti-cataract activity of Pterocarpus marsupium bark and Trigonella foenum-graecum seeds extract in alloxan diabetic rats.
Protective effect of fenugreek (Trigonella foenum graecum) seeds in experimental ethanol toxicity.
[Determination of trigonelline by HPLC and study on its pharmacokinetics].
Mechanism of action of a hypoglycemic principle isolated from fenugreek seeds.
Mitigation of thyroxine-induced hyperglycaemia by two plant extracts.
Immunomodulatory effects of fenugreek (Trigonella foenum graecum L.) extract in mice.
In vitro effect of fenugreek extracts on intestinal sodium-dependent glucose uptake and hepatic glycogen phosphorylase A.
Gastroprotective effect of fenugreek seeds (Trigonella foenum graecum) on experimental gastric ulcer in rats.
Restoration on tissue antioxidants by fenugreek seeds (Trigonella Foenum Graecum) in alloxan-diabetic rats.
Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study.
Evaluation of anti-hyperglycemic and hypoglycemic effect of Trigonella foenum-graecum Linn, Ocimum sanctum Linn and Pterocarpus marsupium Linn in normal and alloxanized diabetic rats.
Hypoglycaemic effect of aqueous extract of the leaves of Trigonella foenum-graecum in healthy volunteers.
Trigonella foenum graecum (fenugreek) seed extract as an antineoplastic agent.
Anti-inflammatory and antipyretic effects of Trigonella foenum-graecum leaves extract in the rat.
Evaluation of the oral hypoglycaemic effect of Trigonella foenum-graecum L. (methi) in normal mice.
Acute intraperitoneal and oral toxicity of the leaf glycosidic extract of Trigonella foenum-graecum in mice.
Hypoglycaemic and antihyperglycaemic effects of Trigonella foenum-graecum leaf in normal and alloxan induced diabetic rats.
Antinociceptive effects of Trigonella foenum-graecum leaves extract.
Allergy to fenugreek (Trigonella foenum graecum).
Characterization of a dioxygenase from Trigonella foenum-graecum involved in 4-hydroxyisoleucine biosynthesis.
Steroid saponins from fenugreek seeds: extraction, purification, and pharmacological investigation on feeding behavior and plasma cholesterol.
Characterization of the hypoglycemic effects of Trigonella foenum graecum seed.
Effects of a fenugreek seed extract on feeding behaviour in the rat: metabolic-endocrine correlates.
The effect of an ethanol extract derived from fenugreek (Trigonella foenum-graecum) on bile acid absorption and cholesterol levels in rats.
Antagonism of cadmium and alloxan-induced hyperglycemia in rats by Trigonella foenum graecum.

Other Information

FDA Listing of Food Additive Status:View
Wikipedia:View

PhysChem Properties

Material listed in food chemical codex No

Organoleptic Properties

Odor Type: Caramellic
fenugreek, caramellic
General comment At 100.00 %. fenugreek
Flavor Type: Caramellic
fenugreek, caramellic
General comment Fenugreek

Occurrences

Safety Information

Safety information

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavoring agents and cosmetic fragrance agents, dietary supplements
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice

Safety references

ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
trigonella foenum-graecum l. extract
Chemidplus:0084625401