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2-octanol

Chemical Structure

General Material Information

Preferred name 2-octanol
Trivial Name 2-Octanol
Short Description methyl hexyl carbinol
Formula C8 H18 O
CAS Number 123-96-6
Deleted CAS Number 113244-40-9
FEMA Number 2801
Flavis Number 2.022
ECHA Number 204-667-0
FDA UNII 66B0DD5E40
Nikkaji Number J9.883C
Beilstein Number 1719322
MDL MFCD00004591
COE Number 71
Bio Activity Summary External link
NMR Predictor External link
JECFA Food Flavoring 289 2-octanol
FDA Patent No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm 123-96-6 ; 2-OCTANOL
Synonyms
  • 2-caprylic alcohol
  • sec- caprylic alcohol
  • hexyl methyl carbinol
  • 2-hydroxy-N-octane
  • 2-hydroxyoctane
  • 1-methyl heptyl alcohol
  • methyl hexyl carbinol
  • 1-methyl-1-heptanol
  • octan-2-ol
  • (1)- octan-2-ol
  • N- octan-2-ol
  • (±)-2-octanol
  • (R,S)-2-octanol
  • (RS)-2-octanol
  • 2-octanol natural
  • 2-octyl alcohol
  • beta- octyl alcohol
  • S- octyl alcohol
  • sec-Caprylic alcohol
  • Hexylmethylcarbinol
  • Methylhexylcarbinol
  • s-Octyl alcohol
  • β-Octyl alcohol
  • 1-Methylheptyl alcohol
  • 2-Octyl alcohol
  • n-Octan-2-ol
  • 2-Hydroxyoctane
  • 2-Hydroxy-n-octane
  • 1-Methyl-1-heptanol
  • 1-Methylheptanol
  • DL-2-Octanol
  • dl-Methylhexylcarbinol
  • (±)-2-Octanol
  • (RS)-2-Octanol
  • NSC 14759

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Literature & References

Leffingwell:Chirality or Article
octan-2-ol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:123-96-6
Pubchem (cid):20083
Pubchem (sid):134974894
Flavornet:123-96-6
Pherobase:View
Publications by PubMed
Improvement of the activation of lipase from Candida rugosa following physical and chemical immobilization on modified mesoporous silica.
Novel Magnetic Cross-Linked Lipase Aggregates for Improving the Resolution of (R, S)-2-octanol.
Electrophysiological responses of the rice leaffolder, Cnaphalocrocis medinalis, to rice plant volatiles.
In vitro determination of volatile compound development during starter culture-controlled fermentation of Cucurbitaceae cotyledons.
Measurement of plasma protein and lipoprotein binding of pyrethroids.
Biocatalytic anti-Prelog reduction of prochiral ketones with whole cells of Acetobacter pasteurianus GIM1.158.
Immobilized Candida antarctica lipase B on ZnO nanowires/macroporous silica composites for catalyzing chiral resolution of (R,S)-2-octanol.
Copper-organic frameworks assembled from in situ generated 5-(4-pyridyl)tetrazole building blocks: synthesis, structural features, topological analysis and catalytic oxidation of alcohols.
Engineering of p450pyr hydroxylase for the highly regio- and enantioselective subterminal hydroxylation of alkanes.
Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose.
Broadband dynamics in neat 4-methyl-3-heptanol and in mixtures with 2-ethyl-1-hexanol.
Bradykinin-induced Ca2+ signaling in human subcutaneous fibroblasts involves ATP release via hemichannels leading to P2Y12 receptors activation.
Anti-arrhythmic effect of verapamil is accompanied by preservation of cx43 protein in rat heart.
How do high pressures change the Debye process of 4-methyl-3-heptanol?
Histamine induces ATP release from human subcutaneous fibroblasts, via pannexin-1 hemichannels, leading to Ca2+ mobilization and cell proliferation.
Role of gap junction-mediated communications in regulating large-scale chromatin configuration remodeling and embryonic developmental competence acquisition in fully grown bovine oocyte.
Improved performance of Yarrowia lipolytica lipase-catalyzed kinetic resolution of (R,S)-2-octanol by an integrated strategy of interfacial activation, bioimprinting and immobilization.
Effect of storage time and heat processing on the volatile profile of Senegalese sole (Solea senegalensis Kaup, 1858) muscle.
Debye relaxation and 250 K anomaly in glass forming monohydroxy alcohols.
Nitric oxide signalling is involved in diarylheptanoid-induced increases in femoral arterial blood flow in ovariectomized rats.
Preparation of polypyrrole composite solid-phase microextraction fiber coatings by sol-gel technique for the trace analysis of polar biological volatile organic compounds.
Novel chiral tool, (R)-2-octanol dehydrogenase, from Pichia finlandica: purification, gene cloning, and application for optically active α-haloalcohols.
Enantiocomplementary Yarrowia lipolytica Oxidoreductases: Alcohol Dehydrogenase 2 and Short Chain Dehydrogenase/Reductase.
Sol-gel entrapped Candida antarctica lipase B--a biocatalyst with excellent stability for kinetic resolution of secondary alcohols.
Structure and mechanism of an inverting alkylsulfatase from Pseudomonas sp. DSM6611 specific for secondary alkyl sulfates.
κ-opioid receptor activation prevents against arrhythmias by preserving Cx43 protein via alleviation of intracellular calcium.
A new biosensor for chiral recognition using goat and rabbit serum albumin self-assembled quartz crystal microbalance.
Immobilization of Pseudomonas fluorescens lipase onto magnetic nanoparticles for resolution of 2-octanol.
Syntheses of enantiopure aliphatic secondary alcohols and acetates by bioresolution with lipase B from Candida antarctica.
Application of hydrogen peroxide encapsulated in silica xerogels to oxidation reactions.
Intensely luminescent homoleptic alkynyl decanuclear gold(I) clusters and their cationic octanuclear phosphine derivatives.
Studies of the gas phase reactions of linalool, 6-methyl-5-hepten-2-ol and 3-methyl-1-penten-3-ol with O3 and OH radicals.
Formation of the aroma of a raw goat milk cheese during maturation analysed by SPME-GC-MS.
Kinetic limitations on tracer partitioning in ganglia dominated source zones.
Evaluation of parallel milliliter-scale stirred-tank bioreactors for the study of biphasic whole-cell biocatalysis with ionic liquids.
Coupling of permeabilized cells of Gluconobacter oxydans and Ralstonia eutropha for asymmetric ketone reduction using H2 as reductant.
The mechanism of injury-induced intracellular calcium concentration oscillations in the endothelium of excised rat aorta.
Synthesis and transformations of di-endo-3-aminobicyclo-[2.2.2]oct-5-ene-2-carboxylic acid derivatives.
Alcohol enhanced permeation in model membranes. Part II. Thermodynamic analysis of membrane partitioning.
Aroma volatiles recovered in the water phase of cashew apple (Anacardium occidentale L.) juice during concentration.
Enhanced activity and enantioselectivity of a hyperthermophilic esterase from archaeon Aeropyrum pernix K1 by acetone treatment.
NOS inhibition synchronizes calcium oscillations in human adipose tissue-derived mesenchymal stem cells by increasing gap-junctional coupling.
Energy transfer from silica core-surfactant shell nanoparticles to hosted molecular fluorophores.
Solvent free oxidation of primary alcohols and diols using thymine iron(III) catalyst.
Effects of T-type calcium channel blockers on cocaine-induced hyperlocomotion and thalamocortical GABAergic abnormalities in mice.
Synthesis and optical properties of BaFBr and BaFBr:Eu2+ nanoparticles.
Influence of pre-cure freezing on the profile of volatile compounds during the processing of Iberian hams.
Spontaneous product segregation from reactions in ionic liquids: application in Pd-catalyzed aliphatic alcohol oxidation.
Purification and characterization of an anti-Prelog alcohol dehydrogenase from Oenococcus oeni that reduces 2-octanone to (R)-2-octanol.
Preparation of (S)-1-Halo-2-octanols Using Ionic Liquids and Biocatalysts.
Behavioral and electrophysiological responses of Triatoma brasiliensis males to volatiles produced in the metasternal glands of females.
A novel strategy for rapid real-time chiral discrimination of enantiomers using serum albumin functionalized QCM biosensor.
Damaging effect of cumulus denudation on rabbit oocytes.
Optimization of poly(GMA-co-EDMA) monolithic support for trypsin nanoreactor fabrication.
Aroma-active components of Lycii fructus (kukija).
Telomerization of butadiene with glycerol: reaction control through process engineering, solvents, and additives.
Activity of essential oils and individual components against acetyl- and butyrylcholinesterase.
[Rapid determination of volatile flavor compounds in soy sauce using head space solid-phase microextraction and gas chromatography-mass spectrometry].
[Synthesis and fluorescence of KznF3 : Ce3+, Tb3+ nanoparticles].
Retraction: (S)-(+)-2-octanol as a chiral oil core for the microemulsion electrokinetic chromatographic separation of chiral basic drugs [Anal. Sci., Vol. 23, p. 1071 (2007)].
Detection of fungal development in closed spaces through the determination of specific chemical targets.
IBMX-elicited inhibition of water permeability in the isolated rabbit conjunctival epithelium.
Deracemization of secondary alcohols through a concurrent tandem biocatalytic oxidation and reduction.
Diastereoselective synthesis of (R)-(alkyl)-beta-D-galactopyranoside by using beta-galactosidase (Aspergillus oryzae) in low-water media.
Determination of alcohol compounds using corona discharge ion mobility spectrometry.
(S)-(+)-2-octanol as a chiral oil core for the microemulsion electrokinetic chromatographic separation of chiral basic drugs.
Epimers of bicyclo[2.2.2]octan-2-ol derivatives with antiprotozoal activity.
Hydrogen bonding in liquid and supercritical 1-octanol and 2-octanol assessed by near and midinfrared spectroscopy.
Comparison of hydrogen bonding in 1-octanol and 2-octanol as probed by spectroscopic techniques.
Kinetic model for reactivity in quaternary water-in-oil microemulsions.
Effect of lipase immobilization on resolution of (R, S)-2-octanol in nonaqueous media using modified ultrastable-Y molecular sieve as support.
Core-shell type of nanoparticles composed of poly[(n-butyl cyanoacrylate)-co-(2-octyl cyanoacrylate)] copolymers for drug delivery application: synthesis, characterization and in vitro degradation.
Anti-prelog reduction of prochiral carbonyl compounds by Oenococcus oeni in a biphasic system.
Preparation of single-enantiomer 2-methyl-4-heptanol, a pheromone of Metamasius hemipterus, using (S)-2-methoxy-2-(1-naphthyl)propionic acid.
Functional characterization of alcohol oxidases from Aspergillus terreus MTCC 6324.
Bicyclo[3.2.1]octa-3,6-dien-2-yl cation: a bishomoantiaromate.
Interactions between acetoin, a plant volatile, and pheromone in Rhynchophorus palmarum: behavioral and olfactory neuron responses.
Studies on the mechanism of Indigo Carmine removal by solvent sublation.
Gibbs energies of transfer of chiral anions across the interface water/chiral organic solvent determined with the help of three-phase electrodes.
Determining the Gibbs energy of ion transfer across water-organic liquid interfaces with three-phase electrodes.
High-yield conversion of (R)-2-octanol from the corresponding racemate by stereoinversion using Candida rugosa.
Photodynamic therapy with PhotoPoint photosensitiser MV6401, indium chloride methyl pyropheophorbide, achieves selective closure of rat corneal neovascularisation and rabbit choriocapillaris.
The nature of the hydrophobic n-alkanol binding site within the C1 domains of protein kinase Calpha.
The stereoselectivity and catalytic properties of Xanthobacter autotrophicus 2-[(R)-2-Hydroxypropylthio]ethanesulfonate dehydrogenase are controlled by interactions between C-terminal arginine residues and the sulfonate of coenzyme M.
A hollow-fiber membrane extraction process for recovery and separation of lactic acid from aqueous solution.
Effects of alcohols and anesthetics on recombinant voltage-gated Na+ channels.
General anesthetic octanol and related compounds activate wild-type and delF508 cystic fibrosis chloride channels.
Oxidative one-carbon cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes.
Regio- and enantioselective alkane hydroxylation with engineered cytochromes P450 BM-3.
Microbial/enzymatic synthesis of chiral drug intermediates.
In situ Ca2+ imaging of odor responses in a coronal olfactory epithelium slice.
(2RS)-5,6:7,8-Dibenzobicyclo[2.2.2]octan-2-ol.
Purification and characterization of an inverting stereo- and enantioselective sec-alkylsulfatase from the gram-positive bacterium Rhodococcus ruber DSM 44541.
Solvent influence on excited-state intramolecular proton transfer in 3-hydroxychromone derivatives studied by cryogenic high-resolution fluorescence spectroscopy.
On the mechanism of the unexpected facile formation of meso-diacetate products in enzymatic acetylation of alkanediols.
Stereocontrolled diels-alder cycloadditions of sugar-derived dihydropyranones with dienes.
Solvent effect on ion-pair extraction of 2-(2-pyridylazo)-1-naphthol-4-sulfonate anion with solvated hydroxonium ion using alcohols and 1-octanol/octane mixed solvents.
Enantioseparation of chiral amino acids as the N(O,S)-ethoxycarbonylated diastereomeric esters by achiral dual-capillary column gas chromatography.
A comparison of lipase-catalysed ester and lactone synthesis in low-water systems: analysis of optimum water activity.
Synthesis of optically active 2-alkoxy-2H-pyran-3(6H)-ones. Their use as dienophiles in Diels-Alder cycloadditions.
Efficient and selective microbial esterification with dry mycelium of Rhizopus oryzae.
Aromatic profile of aqueous banana essence and banana fruit by gas chromatography-mass spectrometry (GC-MS) and gas chromatography-olfactometry (GC-O).
Intramolecular homolytic substitution at selenium: synthesis of novel selenium-containing vitamin E analogues.
Modification of fatty acids changes the flavor volatiles in tomato leaves.
Asymmetric reduction of ketones with catecholborane using 2,6-BODOL complexes of titanium(IV) as catalysts.
Influence of Diffusion on the Kinetics of an Enzyme-Catalyzed Reaction in Gelatin-Based Gels.
Solubilization of meso-tetraphenylporphyrin photosensitizers by substitution with fluorine and with 2,3-dihydroxy-1-propyloxy groups.
In vitro characterization of the oxidative cleavage of the octyl side chain of olanexidine, a novel antimicrobial agent, in dog liver microsomes.
Behavior of frustrated phase in ferroelectric and antiferroelectric liquid crystalline mixtures.
Efficient oxidation of alcohols to carbonyl compounds with molecular oxygen catalyzed by N-hydroxyphthalimide combined with a Co species
Comparative evaluation of four detectors in the high-performance liquid chromatographic analysis of chiral nonaromatic alcohols.
New syntheses of the rice moth and stink bug pheromones by employing (2R, 6S)-7-acetoxy-2,6-dimethyl-1-heptanol as a building block.
An endothelium-derived hyperpolarizing factor distinct from NO and prostacyclin is a major endothelium-dependent vasodilator in resistance vessels of wild-type and endothelial NO synthase knockout mice.
pH Sensitivity of non-synaptic field bursts in the dentate gyrus.
Oxidative cleavage of the octyl side chain of 1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045) in rat and dog liver preparations.
Production, properties and application to nonaqueous enzymatic catalysis of lipase from a newly isolated Pseudomonas strain.
Odour-impact compounds of Gorgonzola cheese.
Stereoselective synthesis of the optically active samin type of lignan from L-glutamic acid.
Characterization of nitric oxide- and prostaglandin-independent relaxation in response to acetylcholine in rabbit renal artery.
Capillary electrochromatography of proteins and peptides with porous-layer open-tubular columns.
Modification of histidine residues by 4,5-epoxy-2-alkenals.
Propionic acid production by extractive fermentation. I. Solvent considerations.
Role of ERAB/L-3-hydroxyacyl-coenzyme A dehydrogenase type II activity in Abeta-induced cytotoxicity.
Similar propagation of SD and hypoxic SD-like depolarization in rat hippocampus recorded optically and electrically.
Factors affecting virus photoinactivation by a series of phenothiazine dyes.
Studies on the interactions of chiral secondary alcohols with rat hydroxysteroid sulfotransferase STa.
Electrogenic hyperpolarization-elicited chloride transporter current in blue cones of zebrafish retinal slices.
Correlation between hydrophobicity of short-chain aliphatic alcohols and their ability to alter plasma membrane integrity.
The Influence of Different Physicochemical Parameters of the Solvent On The Activity and Selectivity of Lipase.
A method for determination of the absolute configuration of chiral glycerol residues in natural products using TEMPO oxidation and characterization of the glyceric acids formed.
Identification and synthesis of new bicyclic acetals from the mountain pine beetle, Dendroctonus ponderosae Hopkins (Col.: Scol.).
Chemical identification, electrophysiological and behavioral activities of the pheromone of Metamasius hemipterus (Coleoptera: Curculionidae).
A Long-Chain Secondary Alcohol Dehydrogenase from Rhodococcus erythropolis ATCC 4277.
Kinetics of acyl transfer reactions in organic media catalysed by Candida antarctica lipase B.
Identification of the D-enantiomer of 2-hydroxyglutaric acid in glutaric aciduria type II.
The metabolism of n-nonane in male Fischer 344 rats.
Universal spectropolarimeter based on overtone circular dichroism measurements in the near-infrared region.
Chiral detection in high-performance liquid chromatography by vibrational circular dichroism.
Does general anesthetic-induced desensitization of the Torpedo acetylcholine receptor correlate with lipid disordering?
Volatile organic chemicals of a shore-dwelling cyanobacterial mat community.
Stereoselectivity of channel inhibition by secondary alkanol enantiomers at nicotinic acetylcholine receptors.
Variation with caste of the mandibular gland secretion in the leaf-cutting antAtta sexdens rubropilosa.
Evaluation of porphyrin characteristics required for photodynamic therapy.
Evaluation of tumour and tissue distribution of porphyrins for use in photodynamic therapy.
Determination of the enantiomeric composition of samples of cocaine by normal-phase high-performance liquid chromatography with UV detection.
Substrate specificity and stereoselectivity of horse liver alcohol dehydrogenase. Kinetic evaluation of binding and activation parameters controlling the catalytic cycles of unbranched, acyclic secondary alcohols and ketones as substrates of the native and active-site-specific Co(II)-substituted enzyme.
Effects of several selected odorants on the sodium- and potassium-dependent adenosine triphosphatase activities of two different chicken olfactory tuberinals.
Reverse enzyme synthesis in microemulsion-based organo-gels.
Host-derived volatiles as attractants and pheromone synergists for driedfruit beetleCarpophilus hemipterus.
Solvent effects in lipase-catalysed transesterification reactions.
Rapid and reversible secretion changes during uncoupling of rat insulin-producing cells.
Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells.
Protein engineering of alcohol dehydrogenases: effects of amino acid changes at positions 93 and 48 of yeast ADH1.
Role of lipid solubility in the interaction of drugs with the N-methyl-D-aspartate receptor.
Biotransformation of alkyl and aryl carbonates. Microbial degradation.
Production of optically active esters and alcohols from racemic alcohols by lipase-catalyzed stereoselective transesterification in non-aqueous reaction system.
Sonochemistry of nitrone spin traps in aqueous solutions. Evidence for pyrolysis radicals from spin traps.
Enzymatic transesterification with the lipase from Pseudomonas fragi 22.39 B in a non-aqueous reaction system.
[The effects of heptaminol chlorhydrate on neuromuscular transmission].
Seed-germination inhibition by volatile alcohols and other compounds associated withAmaranthus palmeri residues.
Observations concerning the nature of sites of anaesthetic action in Gammarus.
A new immobilized cell system with protection against toxic solvents.
Determination of alpha-alkyl-alpha-amino acids and alpha-amino alcohols by chiral-phase capillary gas chromatography and reverse-phase high-performance liquid chromatography.
Kinetic resolution of secondary alcohols with commercial lipases : Application to rootworm sex pheromone synthesis.
Identification of volatile allelochemicals fromAmaranthus palmeri S. Wats.
Anesthetic potencies of secondary alcohol enantiomers.
The metabolism of n-octane in Fischer 344 rats.
Identification of the n-heptane metabolites in rat and human urine.
Accumulation and drainage of hemin in the red cell membrane.
Preparative resolution of D,L-threonine catalyzed by immobilized phosphatase.
Receptor cell responses to odorants: similarities and differences among odorants.
Structure-activity correlations among analogs of 4-methyl-3-heptanol, a pheromone component of the european elm bark beetle (Scolytus multistriatus).
Field response of the dutch elm disease vectors,Scolytus multistriatus (Marsham) andS. scolytus (F.) (Coleoptera: Scolytidae) to 4-methyl-3-heptanol baits containing α-, β-,δ-, or δ-multistriatin.
Alarm responses caused by newly identified compounds derived from the honeybee sting.
Insecticidal effect of aliphatic alcohols against aquatic stages of Aedes mosquitoes.
Electroantennogram responses ofScolytus multistriatus (Coleoptera: Scolytidae) to its pheromone components and to associated compounds.
Investigations into falsely elevated somatic cell counts of bulked herd milk.
Alcohol dehydrogenase from the fruitfly Drosophila melanogaster. Substrate specificity of the alleloenzymes AdhS and AdhUF.
The estimation of low levels of 14C in biological samples by alkaline extraction and liquid scintillation counting.
Gas-chromatographic resolution of enantiomeric secondary alcohols. Stereoselective reductive metabolism of ketones in rabbit-liver cytosol.
Soldier defense secretions ofTrinervitermes bettonianus (Isoptera, Nasutitermitinae): Chemical variation in allopatric populations.
Absorption, distribution, elimination and metabolism of 14C-heptaminol hydrochloride in rat.
Enantiomeric purity of naproxen by liquid chromatographic analysis of its diastereomeric octyl esters.
Electronic properties of the nitrosamine function.
A novel mechanism of enzymic ester hydrolysis. Inversion of configuration and carbon-oxygen bond cleavage by secondary alkylsulphohydrolases from detergent-degrading micro-organisms.
Identification of volatile compounds in hybrids between raspberry (Rubus idaeus, L.) and arctic bramble (Rubus arciticus, L.).
Ligand-induced structural changes in amylose partially complexed with iodine.
Extraction method and thin-layer chromatographic system for the determination of alpha-l-acetylmethadol and metabolites in biological fluids.
[Determination of 6-amino-2-methyl-heptanol-(2) as the 1-dimethylaminonaphthaline-5-sulfonic acid amide].
Novel method of configurational correlation: (+)-sedridine and S-(+)-octan-2-ol.
Serological diagnosis of amoebiasis by immunofluorescence.
The specificities and configurations of ternary complexes of yeast and liver alcohol dehydrogenases.
Alterations in serum proteins following delipidization by 2-octanol.
THE EXTRACTION OF LIPIDS FROM HUMAN PLASMA OR SERUM BY 2-OCTANOL.
The action of 267C (1-(1-piperidyl)-6-methyl-3-phenyl-3-heptanol hydrochloride) in Parkinson's disease.
[Pharmacodynamic study of 6-amino-2-methyl-2-heptanol hydrochloride (heptaminol hydrochloride or R.P. 2831). II. Action of heptaminol hydrochloride on diuresis in the dog].
[Pharmacodynamic study of 6-amino-2-methyl-2-heptanol hydrochloride (heptaminol hydrochloride or R. P. 2831). I. Action of heptaminol hydrochloride on the cardiovascular and central nervous systems].
[Action of 6-amino-2-methyl-2-heptanol in the treatment of various experimental cardiovascular shock states].
Equilibrium studies on the dehydrogenation of primary and secondary alcohols; 2-butanol, 2-octanol, cyclopentanol and benzyl alcohol.

Other Information

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
FooDB:FDB012584
Export Tariff Code:2905.16.0050
Typical G.C.
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
grades: technical 92-99%; pure.

PhysChem Properties

Material listed in food chemical codex No
Molecular weight 130.23066711426
Specific gravity @ 25 °C
Pounds per Gallon 6.74 to 6.823
Refractive Index 1.418 to 1.428 @ 20 °C
Melting Point -38 to -37°C @ 760 mm Hg
Boiling Point 179 to 181°C @ 760 mm Hg
Vapor Pressure 0.306 mmHg @ 25 °C
Flash Point TCC Value 71.11 °C TCC
logP (o/w) 2.9
Solubility
alcohol Yes
dipropylene glycol Yes
water, 990.9 mg/L @ 25 °C (est) Yes
water, 1120 mg/L @ 25 °C (exp) Yes

Organoleptic Properties

Odor Type: Spicy
fresh, spicy, green, woody, herbal, earthy
Odor strength medium , recommend smelling in a 10.00 % solution or less
Substantivity 12 hour(s) at 100.00 %
Luebke, William tgsc, (1986) At 10.00 % in dipropylene glycol. fresh spicy green woody herbal earthy
Flavor Type: Spicy
herbal, spicy, green, nasturtium, earthy, banana unripe banana, mushroom
Luebke, William tgsc, (1986) Herbal spicy green nasturtium earthy unripe banana mushroom

Occurrences

Potential Uses

Applications
Odor purposes Earth , Geranium , Green , Herbal , Lavender , Mint , Spice , Woody
Cosmetic purposes Perfuming agents

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
R 41 - Risk of serious damage to eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 3200 mg/kg
(Patty et al., 1935)

unreported-mammal (species unspecified) LD50 6934 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(5), Pg. 61, 1986.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2-octanol usage levels up to:
1.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU): 11.00 (μg/capita/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -4.00000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.60000
fruit ices: -0.60000
gelatins / puddings: -2.00000
granulated sugar: --
gravies: --
hard candy: -3.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --

Safety references

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 7 (FGE.07): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
View page or View pdf

Flavouring Group Evaluation 7, Revision 1 (FGE.07Rev1): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission
View page or View pdf

Flavouring Group Evaluation 7, Revision 2 (FGE.07Rev2) : Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5
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Safety and efficacy of saturated and unsaturated aliphatic secondary alcohols, ketones and esters with esters containing secondary alcohols belonging to chemical group 5 when used as flavourings for all animal species
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octan-2-ol
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