dextro-sorbitol

General Material Information

Preferred name	dextro-sorbitol
Trivial Name	Sorbitol
Short Description	(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol
Formula	C6 H14 O6
CAS Number	50-70-4
Deleted CAS Number	15060-73-8
FEMA Number	3029
ECHA Number	200-061-5
FDA UNII	506T60A25R
Nikkaji Number	J2.299C
Beilstein Number	1721899
MDL	MFCD00004708
Bio Activity Summary	External link
NMR Predictor	External link
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	50-70-4 ; D-SORBITOL
Synonyms	(2R,3R,4R,5S)-hexan-1,2,3,4,5,6-hexol (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol cholaxine cystosol D-sorbol D-(-)-sorbitol D-1,2,3,4,5,6-hexane hexol D-1,2,3,4,5,6-hexanehexol D-galactitol D-glucitol D-sorbit D-sorbitol dextro-(-)-sorbitol dextro-1,2,3,4,5,6-hexane hexol dextro-1,2,3,4,5,6-hexanehexol dextro-glucitol dextro-sorbitol natural diakarmon esasorb foodol D 70 karion kyowa powder 50M multitol neosorb 20/60DC neosorb 70/02 neosorb 70/70 neosorb P 20/60 neosorb P 60 neosorb P 60W nevitin nivitin probilagol resulax sionit sionit K sionon siosan SOR sorbex M sorbex R sorbex S sorbex X sorbicolan sorbilande sorbilax sorbit sorbit D 70 sorbit D-powder sorbit DP sorbit DP 50 sorbit L 70 sorbit S sorbit T 70 sorbit W 70 sorbit W-powder sorbit WP sorbitol crystalline, coarse sorbitol crystalline, gran sorbitol crystalline, pwd sorbitol crystalline, technical coarse powder sorbitol crystalline, technical granular sorbitol crystalline, technical powder sorbitol F sorbitol FK sorbitol FP sorbitol powder food grade sorbitol powder NF grade sorbitol S sorbitol syrup C sorbo sorbol Glucitol, D- Sorbitol L-Gulitol Neosorb Sorbex Rp Sorbostyl Sionite Karion (carbohydrate) Glucitol Karion instant (-)-Sorbitol Sorbite Glucarine (sorbitol syrup) Glucarine CSorbidex Sorbidex P 16616 Sorbit Kyowa Powder 50M Sorbitur E 420 Sorbogem 712 Sorbit W-Powder 50 NSC 25944 CSorbidex P 16616 D-Sorbit 50M 7B5697N Cerestar P 16616 P 60W Sorbidex S 16601 Neosorb 70/20 LTS-P 20M Sorbit LTSP Sorbit D C*Sorbidex 16100 CSorbidex 16100 Sorbitol Kao Neosorb 70/02SB Sorbitol SP Sorbidex NC 16205 Parteck SI 150 Sorbitol 70W Sorpart Sorbierite Sorbidex 200 Sorbidex S 16603 LTS P 50M Neosorb 71/02SB Neosorb 70/02B Parteck SI 200 Parteck SI 400 Parteck SI 450 Meritol 121 Sorbitol FP 100M FP 100M Sorbit KK Meritol 128 Merisorb 200 Sorbit KK Powder 50M Foodol 70 Brix 70 LTS-P G 3 Sorbitol Ueno 20M Sorbitol C A 5178 D-SORB 88 Plastilys Neosorb P 650 MeSH ID: D013012 Neosorb P 100T Sorbitol-T Sorbidex P 16656 HS 6903 Neosorb P 200SD

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Literature & References

	(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	50-70-4
Pubchem (cid):	5780
Pubchem (sid):	134971781

Publications by Google Patents
Sorbitol - modified flavor
Publications by PubMed
Stepwise metabolic engineering of Gluconobacter oxydans WSH-003 for the direct production of 2-keto-L-gulonic acid from D-sorbitol.
Acetobacter sicerae sp. nov., isolated from cider and kefir and identification of Acetobacter species by dnaK , groEL and rpoB sequence analysis.
Novel poly(ethylene glycol) gel electrolytes prepared using self-assembled 1,3:2,4-dibenzylidene-D-sorbitol.
[Determination of alditols in foods by ion chromatography-mass spectrometry].
Characterization of new polyol/H+ symporters in Debaryomyces hansenii.
Genotype to phenotype: identification of diagnostic vibrio phenotypes using whole genome sequences.
Concurrent solution-like decoloration rate and high mechanical strength from polymer-dispersed photochromic organogel.
Gluconobacter cerevisiae sp. nov., isolated from the brewery environment.
Best combination of promoter and micellar catalyst for the rapid conversion of sorbitol to glucose.
Industrial Production of L-Ascorbic Acid (Vitamin C) and D-Isoascorbic Acid.
[Method of quantitative analysis by HPLC and confirmation by LC-MS of sugar alcohols in foods].
Viscous conductive glue layer in semitransparent polymer-based solar cells fabricated by a lamination process.
Isolation, characterization and evaluation of the Pichia pastoris sorbitol dehydrogenase promoter for expression of heterologous proteins.
An L-glucitol oxidizing dehydrogenase from Bradyrhizobium japonicum USDA 110 for production of D-sorbose with enzymatic or electrochemical cofactor regeneration.
Intravenous immunoglobulins: in-depth review of excipients and acute kidney injury risk.
Effect of freeze-drying, cryoprotectants and storage conditions on the stability of secondary structure of insulin-loaded solid lipid nanoparticles.
Glassy dynamics of sorbitol solutions at terahertz frequencies.
[Effect of storage temperature on gelation of oral methylcellulose formulation].
Pseudomonas asturiensis sp. nov., isolated from soybean and weeds.
Asticcacaulis solisilvae sp. nov., isolated from forest soil.
Renewable feedstocks in green solvents: thermodynamic study on phase diagrams of D-sorbitol and xylitol with dicyanamide based ionic liquids.
The use of the mechanical microenvironment of phospholipid polymer hydrogels to control cell behavior.
Chitin hydrolysis assisted by cell wall degrading enzymes immobilized of Thichoderma asperellum on totally cinnamoylated D-sorbitol beads.
Effects of salt on the gelation mechanism of a D-sorbitol-based hydrogelator.
Reagentless D-sorbitol biosensor based on D-sorbitol dehydrogenase immobilized in a sol-gel carbon nanotubes-poly(methylene green) composite.
Preparation of D-gulose from disaccharide lactitol using microbial and chemical methods.
Synergistic gelation of silica nanoparticles and a sorbitol-based molecular gelator to yield highly-conductive free-standing gel electrolytes.
Cloning and characterization of a novel NAD+ -dependent xylitol dehydrogenase from Gluconobacter oxydans CGMCC 1. 637.
Characterization of genes involved in D-sorbitol oxidation in thermotolerant Gluconobacter frateurii.
Dissolution-guided wetting for microarray and microfluidic devices.
Functional assignment of gene AAC16202.1 from Rhodobacter capsulatus SB1003: new insights into the bacterial SDR sorbitol dehydrogenases family.
In situ synthesis of twelve dialkyltartrate-boric acid complexes and two polyols-boric acid complexes and their applications as chiral ion-pair selectors in nonaqueous capillary electrophoresis.
L-xylo-3-hexulose reductase is the missing link in the oxidoreductive pathway for D-galactose catabolism in filamentous fungi.
Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set.
Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells.
Intracellular expression and purification of the Canstatin-N protein in Pichia pastoris.
A T-shaped amphiphilic molecule forms closed vesicles in water and bicelles in mixtures with a membrane lipid.
Lipase-mediated synthesis of water-soluble plant stanol derivatives in tert-butanol.
Pronounced microheterogeneity in a sorbitol-water mixture observed through variable temperature neutron scattering.
High-temperature sorbose fermentation with thermotolerant Gluconobacter frateurii CHM43 and its mutant strain adapted to higher temperature.
Twisted mannitol crystals establish homologous growth mechanisms for high-polymer and small-molecule ring-banded spherulites.
In-hospital outcomes and cost assessment between bipolar versus monopolar transurethral resection of the prostate.
Oral liquid in situ gelling methylcellulose/alginate formulations for sustained drug delivery to dysphagic patients.
Sorbitol dehydrogenase of Aspergillus niger, SdhA, is part of the oxido-reductive D-galactose pathway and essential for D-sorbitol catabolism.
Parabacteroides chartae sp. nov., an obligately anaerobic species from wastewater of a paper mill.
Durable cofactor immobilization in sol-gel bio-composite thin films for reagentless biosensors and bioreactors using dehydrogenases.
Spherical phospholipid polymer hydrogels for cell encapsulation prepared with a flow-focusing microfluidic channel device.
Amphibacillus cookii sp. nov., a facultatively aerobic, spore-forming, moderately halophilic, alkalithermotolerant bacterium.
Differential expression and modification of proteins during ontogenesis in Malus domestica.
Quantitative analysis of dehydration in porcine skin for assessing mechanism of optical clearing.
Multiscale-tailored bioelectrode surfaces for optimized catalytic conversion efficiency.
Effect of hydrophobicity of monomers on the structures and properties of 1,3:2,4-dibenzylidene-D-sorbitol organogels and polymers prepared by templating the gels.
Thermal behavior and crystal structure of poly(L-lactic acid) with 1,3:2,4-dibenzylidene-D-sorbitol.
Levansucrases from Pseudomonas syringae pv. tomato and P. chlororaphis subsp. aurantiaca: substrate specificity, polymerizing properties and usage of different acceptors for fructosylation.
Formulation and evaluation of reconstitutable suspensions containing ibuprofen-loaded Eudragit microspheres.
Enzymatic synthesis of novel branched sugar alcohols mediated by the transglycosylation reaction of pullulan-hydrolyzing amylase II (TVA II) cloned from Thermoactinomyces vulgaris R-47.
Analysis of metabolism of 6FDG: a PET glucose transport tracer.
Factors affecting the electrochemical regeneration of NADH by (2,2'-bipyridyl) (pentamethylcyclopentadienyl)-rhodium complexes: impact on their immobilization onto electrode surfaces.
Proteomic analysis of the secretory response of Aspergillus niger to D-maltose and D-xylose.
Synthesis and characterization of poly-O-methyl-[n]-polyurethane from a d-glucamine-based monomer.
Enhanced enantioselective recognition with diastereoisomeric BINOL based chiral fluorescent boronic acid sensors.
Efficient conversion of d-glucose into d-sorbitol over MCM-41 supported Ru catalyst prepared by a formaldehyde reduction process.
Drosophila evaluates and learns the nutritional value of sugars.
A comprehensive evaluation of the toxicology of cigarette ingredients: carbohydrates and natural products.
Participation of the urokinase-type plasminogen activator receptor (uPAR) in neutrophil transendothelial migration.
Characterization of a Chromobacterium haemolyticum population from a natural tropical lake.
An ultrasonication-assisted extraction and derivatization protocol for GC/TOFMS-based metabolite profiling.
Classification of avian haemolytic Actinobacillus-like organisms (Bisgaard taxon 26) associated with anseriforme birds as Actinobacillus anseriformium sp. nov.
In situ gelling formulation based on methylcellulose/pectin system for oral-sustained drug delivery to dysphagic patients.
A hyaluronic acid dispersed carbon nanotube electrode used for a mediatorless NADH sensing and biosensing.
The crystal structure of l-sorbose reductase from Gluconobacter frateurii complexed with NADPH and l-sorbose.
Erwinia oleae sp. nov., isolated from olive knots caused by Pseudomonas savastanoi pv. savastanoi.
Determination of 195 pesticide residues in Chinese herbs by gas chromatography-mass spectrometry using analyte protectants.
Synthesis, carbohydrate- and DNA-binding studies of cationic 2,2':6',2''-terpyridineplatinum(II) complexes containing N- and S-donor boronic acid ligands.
Use of a Gluconobacter frateurii mutant to prevent dihydroxyacetone accumulation during glyceric acid production from glycerol.
Effect of D-sorbitol on the thermal gelation of methylcellulose formulations for drug delivery.
Cloning, heterologous expression, and characterization of the xylitol and L-arabitol dehydrogenase genes, Texdh and Telad, from the thermophilic fungus Talaromyces emersonii.
Synthesis and glycosidase inhibitory activity of 1-amino-3,6-anhydro-1-deoxy-D-sorbitol derivatives.
A novel carbon source-dependent genetic transformation system for the versatile cell factory Hypocrea jecorina (anamorph Trichoderma reesei).
[Chemical constituents from fruits of Ailanthus altissima].
Noninvasive functional liver blood flow measurement: comparison between bolus dose and steady-state clearance of sorbitol in a small-rodent model.
Clostridium arbusti sp. nov., an anaerobic bacterium isolated from pear orchard soil.
[Transcription profile of PfRON4 gene in Plasmodium falciparum erythrocytic stage].
Reactivity of poly-alcohols towards OH, NO3 and SO4- in aqueous solution.
Molecular dynamics studies of the conformation of sorbitol.
Imaging chiroptical artifacts.
Effect of organic modifiers on the structure of nickel nanoparticles and catalytic activity in the hydrogenation of p-nitrophenol to p-aminophenol.
A single amino acid change (Y318F) in the L-arabitol dehydrogenase (LadA) from Aspergillus niger results in a significant increase in affinity for D-sorbitol.
Effects of cryoprotectant treatments on bovine sperm function and osmolyte content.
Serratia glossinae sp. nov., isolated from the midgut of the tsetse fly Glossina palpalis gambiensis.
Host-guest interactions of 5-fluorouracil in supramolecular organogels.
Multiresidue determination of 11 new fungicides in grapes and wines by liquid-liquid extraction/clean-up and programmable temperature vaporization injection with analyte protectants/gas chromatography/ion trap mass spectrometry.
Coordinated surface activities in Variovorax paradoxus EPS.
Functional hepatic flow can predict the hepatic reserve function in surgical cirrhotic patients.
Off-line FIA monitoring of D-sorbitol consumption during L-sorbose production using a sorbitol biosensor.
Use of spermine and thiabendazole as analyte protectants to improve direct analysis of 16 carbamates by gas chromatography-mass spectrometry in green vegetable matrices.
Providencia sneebia sp. nov. and Providencia burhodogranariea sp. nov., isolated from wild Drosophila melanogaster.
Compaction properties of isomalt.
Contribution of the T1r3 taste receptor to the response properties of central gustatory neurons.
Farnesol-modified biodegradable polyurethanes for cartilage tissue engineering.
Thermo-reversibility of the fluorescence enhancement of acridine orange induced by supramolecular self-assembly.
Direct production of L-tagatose from L-psicose by Enterobacter aerogenes 230S.
Syntheses of retinol glycosides using beta-glucosidase in SCCO(2) media.
Determination of boron as boric acid in eye lotions using a sequential injection system.
Syntheses of dopa glycosides using glucosidases.
A green route to water soluble carbon nanotubes and in situ loading of silver nanoparticles.
Compressibility of gastroretentive pellets coated with Eudragit NE using a single-stroke and a rotary tablet press.
Orientational dependence of linear dichroism exemplified by dyed spherulites.
Lipophilic polymer membrane optical sensor with a synthetic receptor for saccharide detection.
Inhibitory action of palatinose and its hydrogenated derivatives on the hydrolysis of alpha-glucosylsaccharides in the small intestine.
Angiotensin-converting enzyme inhibitory and antioxidant activities of enzymatically synthesized phenolic and vitamin glycosides.
Influence of additives on adhesion of Penicillium frequentans conidia to peach fruit surfaces and relationship to the biocontrol of brown rot caused by Monilinia laxa.
Membrane-bound pyrroloquinoline quinone-dependent dehydrogenase in Gluconobacter oxydans M5, responsible for production of 6-(2-hydroxyethyl) amino-6-deoxy-L-sorbose.
Removal and prevention of dental plaque with d-tagatose.
Humectancies of d-tagatose and d-sorbitol.
A pyrroloquinoline quinine-dependent membrane-bound d-sorbitol dehydrogenase from Gluconobacter oxydans exhibits an ordered Bi Bi reaction mechanism.
Determination of 23 pesticide residues in leafy vegetables using gas chromatography-ion trap mass spectrometry and analyte protectants.
Distinct physiological roles of two membrane-bound dehydrogenases responsible for D-sorbitol oxidation in Gluconobacter frateurii.
Immobilization of recombinant invertase (re-INVB) from Zymomonas mobilis on D-sorbitol cinnamic ester for production of invert sugar.
Enterobacter pulveris sp. nov., isolated from fruit powder, infant formula and an infant formula production environment.
Nerve regeneration using tubular scaffolds from biodegradable polyurethane.
Temperature-sensitive aqueous surfactant two-phase system formation in cationic-anionic surfactant systems.
Cloning, characterization, and mutational analysis of a highly active and stable L-arabinitol 4-dehydrogenase from Neurospora crassa.
Effects of the immobilization supports on the catalytic properties of immobilized mushroom tyrosinase: a comparative study using several substrates.
Membrane-bound, 2-keto-D-gluconate-yielding D-gluconate dehydrogenase from "Gluconobacter dioxyacetonicus" IFO 3271: molecular properties and gene disruption.
Chemical constituents from leaves of Celastrus gemmatus Loes.
Avibacterium endocarditidis sp. nov., isolated from valvular endocarditis in chickens.
An integrated procedure for the measurement of total dietary fibre (including resistant starch), non-digestible oligosaccharides and available carbohydrates.
The use of long-chain plant polyprenols as a means to modify the biological properties of new biodegradable polyurethane scaffolds for tissue engineering. A pilot study.
Stereospecificity of mushroom tyrosinase immobilized on a chiral and a nonchiral support.
Bacillus decisifrondis sp. nov., isolated from soil underlying decaying leaf foliage.
L-sorbose reductase and its transcriptional regulator involved in L-sorbose utilization of Gluconobacter frateurii.
Effect of physical aging on the Johari-Goldstein and alpha relaxations of D-sorbitol: a study by thermally stimulated depolarization currents.
Paenibacillus zanthoxyli sp. nov., a novel nitrogen-fixing species isolated from the rhizosphere of Zanthoxylum simulans.
Enterobacter turicensis sp. nov. and Enterobacter helveticus sp. nov., isolated from fruit powder.
High-throughput microplate enzymatic assays for fast sugar and acid quantification in apple and tomato.
Alfentanil-induced miosis as a surrogate measure of alfentanil pharmacokinetics in patients with mild and moderate liver cirrhosis.
Synthesis of macrolide-saccharide hybrids by ring-closing metathesis of precursors derived from glycitols and benzoic acids.
Correlation of primary relaxations and high-frequency modes in supercooled liquids. II. Evidence from spin-lattice relaxation weighted stimulated-echo spectroscopy.
Molecular cloning and characterization of NAD(+)-dependent xylitol dehydrogenase from Candida tropicalis ATCC 20913.
Purification and characterization of a nitrilase from Aspergillus niger K10.
Medium effects on zwitterionic-biradicaloid intermediates from two phenyl-alpha-oxoamides. Irradiations in fluid and solid protic media, neat solid phases, and the solid, smectic and isotropic phases of a completely saturated phosphonium salt at different temperatures.
Origin of enhanced crystal growth kinetics near Tg probed with indomethacin polymorphs.
Effect of stabilizers on the shelf-life of Penicillium frequentans conidia and their efficacy as a biological agent against peach brown rot.
A model system for increasing the intensity of whole-cell biocatalysis: investigation of the rate of oxidation of D-sorbitol to L-sorbose by thin bi-layer latex coatings of non-growing Gluconobacter oxydans.
Preliminary studies on the inhibition of D-sorbitol-6-phosphate 2-dehydrogenase from Escherichia coli with substrate analogues.
Biodegradable porous polyurethane scaffolds for tissue repair and regeneration.
Differential expression profiles of Streptococcus mutans ftf, gtf and vicR genes in the presence of dietary carbohydrates at early and late exponential growth phases.
Direct immobilization of tyrosinase enzyme from natural mushrooms (Agaricus bisporus) on D-sorbitol cinnamic ester.
Glycosides and amino acyl esters of carbohydrates as potent inhibitors of angiotensin converting enzyme.
Increased NaCl-induced interleukin-8 production by human bronchial epithelial cells is enhanced by the DeltaF508/W1282X mutation of the cystic fibrosis transmembrane conductance regulator gene.
[Endoscopic trigonoplasty II for primary vesico-ureteral reflux].
A new class of glucosidase inhibitor: analogues of the naturally occurring glucosidase inhibitor salacinol with different ring heteroatom substituents and acyclic chain extension.
Study of the polyol pathway in the porcine epididymis.
Global carbon utilization profiles of wild-type, mutant, and transformant strains of Hypocrea jecorina.
Kinetics of spontaneous change in the localized motions of D-sorbitol glass.
The influence of gastric acidity and taste masking agent on in situ gelling pectin formulations for oral sustained delivery of acetaminophen.
Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose.
Daily intake assessment of saccharin, stevioside, D-sorbitol and aspartame from various processed foods in Korea.
Carbohydrate rod conjugates: ternary rod-coil molecules forming complex liquid crystal structures.
Self-assembly and morphology of gel networks in l,3:2,4-bis-O-(p-methylbenzylidene)-D-sorbitol/n-dibutylphthalate.
Production of L-talitol from L-psicose by Metschnikowia koreensis LA1 isolated from soy sauce mash.
Production of L-erythrose via L-erythrulose from erythritol using microbial and enzymatic reactions.
Metabolic engineering study on the direct fermentation of 2-keto-L-gulonic acid, a key intermediate of L-ascorbic acid in Pseudomonas putida IFO3738.
Cloning of a gene for D-sorbitol dehydrogenase from Gluconobacter oxydans G624 and expression of the gene in Pseudomonas putida IFO3738.
Prevotella multisaccharivorax sp. nov., isolated from human subgingival plaque.
Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization.
Use of automated direct sample introduction with analyte protectants in the GC-MS analysis of pesticide residues.
Sorbitol synthesis by an engineered Lactobacillus casei strain expressing a sorbitol-6-phosphate dehydrogenase gene within the lactose operon.
Enterobacter hormaechei subsp. oharae subsp. nov., E. hormaechei subsp. hormaechei comb. nov., and E. hormaechei subsp. steigerwaltii subsp. nov., three new subspecies of clinical importance.
Molecular properties of membrane-bound FAD-containing D-sorbitol dehydrogenase from thermotolerant Gluconobacter frateurii isolated from Thailand.
Pharmacokinetics of levetiracetam in patients with moderate to severe liver cirrhosis (Child-Pugh classes A, B, and C): characterization by dynamic liver function tests.
Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers.
Gluconobacter oxydans NAD-dependent, D-fructose reducing, polyol dehydrogenases activity: screening, medium optimisation and application for enzymatic polyol production.
Characterization of the AXDH gene and the encoded xylitol dehydrogenase from the dimorphic yeast Arxula adeninivorans.
Microbial production of L-ascorbic acid from D-sorbitol, L-sorbose, L-gulose, and L-sorbosone by Ketogulonicigenium vulgare DSM 4025.
Growth and characterisation of primary bovine colon epithelial cells in vitro.
The crystal structure of rabbit phosphoglucose isomerase complexed with D-sorbitol-6-phosphate, an analog of the open chain form of D-glucose-6-phosphate.
Effect of physical exercise on human preference for solutions of various sweet substances.
Clinical and laboratory features of Mycobacterium porcinum.
Mycobacterium cosmeticum sp. nov., a novel rapidly growing species isolated from a cosmetic infection and from a nail salon.
Mild detergent treatment of Candida tropicalis reveals a NADPH-dependent reductase in the crude membrane fraction, which enables the production of pure bicyclic exo-alcohol.
Acute renal failure and intravenous immune globulin: occurs with sucrose-stabilized, but not with D-sorbitol-stabilized, formulation.
AL-12182, a novel 11-oxa prostaglandin analog with topical ocular hypotensive activity in the monkey.
Basic toxicology and metabolism studies of 1,5-anhydro-D-fructose using bacteria, cultured mammalian cells, and rodents.
Application of NAD-dependent polyol dehydrogenases for enzymatic mannitol/sorbitol production with coenzyme regeneration.
Comparison in fractal dimension between those obtained from structure factor and viscoelasticity of gel networks of 1,3:2,4-bis-O-(p-methylbenzylidene)-D-sorbitol in polystyrene melt at gel point.
Johari-Goldstein relaxation and crystallization of sorbitol to ordered and disordered phases.
A new type of square columnar liquid crystalline phases formed by facial amphiphilic triblock molecules.
Detection of RNA in purified cytomegalovirus virions.
[Changes in serum Na+ and blood hemoglobin levels during three types of transurethral procedures for the treatment of benign prostatic hypertrophy].
The metabolic role and evolution of L-arabinitol 4-dehydrogenase of Hypocrea jecorina.
Functional hepatic flow in patients with liver cirrhosis.
[Spinal anesthesia in a patient with hemiparesis after poliomyelitis].
Gelation behaviors of schizophyllan-sorbitol aqueous solutions.
Physical organogels composed of amphiphilic block copolymers and 1,3:2,4-dibenzylidene-D-sorbitol.
D-xylose metabolism in Hypocrea jecorina: loss of the xylitol dehydrogenase step can be partially compensated for by lad1-encoded L-arabinitol-4-dehydrogenase.
In vitro cytotoxic effects of stabilizing sugars within human intravenous immunoglobulin preparations against the human macrophage THP-1 cell-line.
Evaluation of liver functional reserve by combining D-sorbitol clearance rate and CT measured liver volume.
Attenuated total reflectance Fourier transform mid-infrared spectroscopic quantification of sorbitol and sorbose during a Gluconobacter biotransformation process.
[Evaluating liver functional reserve by combining D-sorbitol with indocyanine green measurement].
Escherichia albertii sp. nov., a diarrhoeagenic species isolated from stool specimens of Bangladeshi children.
Enterococcus phoeniculicola sp. nov., a novel member of the enterococci isolated from the uropygial gland of the Red-billed Woodhoopoe, Phoeniculus purpureus.
Nucleation of one polymorph by another.
Effect of glucose on assimilatory sulphate reduction in Arabidopsis thaliana roots.
Membrane-bound D-sorbitol dehydrogenase of Gluconobacter suboxydans IFO 3255--enzymatic and genetic characterization.
New quinoproteins in oxidative fermentation.
5-keto-D-gluconate production is catalyzed by a quinoprotein glycerol dehydrogenase, major polyol dehydrogenase, in gluconobacter species.
New developments in oxidative fermentation.
Genetic relationships among avian isolates classified as Pasteurella haemolytica, 'Actinobacillus salpingitidis' or Pasteurella anatis with proposal of Gallibacterium anatis gen. nov., comb. nov. and description of additional genomospecies within Gallibacterium gen. nov.
Crystal structure of Pseudomonas fluorescens mannitol 2-dehydrogenase: evidence for a very divergent long-chain dehydrogenase family.
Characterization of recombinant xylitol dehydrogenase from Galactocandida mastotermitis expressed in Escherichia coli.
A new endoscopic ureteral reimplantation for primary vesicoureteral reflux (endoscopic trigonoplasty II).
[Production of vitamin C precursor--2-keto-L-gulonic acid from D-sorbitol by mixed culture of microorganisms].
[Enzymatic synthesis of saccharide and saccharide alcohol fatty acid esters].
[Studies on non-anthraquinones in Rheum officinale Baill].
Main polyol dehydrogenase of Gluconobacter suboxydans IFO 3255, membrane-bound D-sorbitol dehydrogenase, that needs product of upstream gene, sldB, for activity.
Staphylococcus succinus subsp. casei subsp. nov., a dominant isolate from a surface ripened cheese.
Insoluble powder formulation as an effective nasal drug delivery system.
Cross-talk between the L-sorbose and D-sorbitol (D-glucitol) metabolic pathways in Lactobacillus casei.
Final classification of Bisgaard taxon 9 as Actinobacillus arthritidis sp. nov. and recognition of a novel genomospecies for equine strains of Actinobacillus lignieresii.
Synthesis of (+)-polyoxamic acid and D-sorbitol from simple achiral allylic halides employing (S,S)-hydrobenzoin as a chiral source.
The missing link in the fungal L-arabinose catabolic pathway, identification of the L-xylulose reductase gene.
Time evolution of dynamic shear moduli in a physical gelation process of 1,3:2,4-bis-O-(p-methylbenzylidene)-D-sorbitol in polystyrene melt: critical exponent and gel strength.
Molecular cloning and functional expression of D-sorbitol dehydrogenase from Gluconobacter suboxydans IF03255, which requires pyrroloquinoline quinone and hydrophobic protein SldB for activity development in E. coli.
Tributyrin and lactitol synergistically enhanced the trophic status of the intestinal mucosa and reduced histamine levels in the gut of nursery pigs.
Purification and properties of membrane-bound D-sorbitol dehydrogenase from Gluconobacter suboxydans IFO 3255.
Membrane-bound quinoprotein D-arabitol dehydrogenase of Gluconobacter suboxydans IFO 3257: a versatile enzyme for the oxidative fermentation of various ketoses.
NADPH-dependent L-sorbose reductase is responsible for L-sorbose assimilation in Gluconobacter suboxydans IFO 3291.
Determination of aldose reductase activity in the eye by localized magnetic resonance spectroscopy.
Determination of D-sorbitol in human erythrocytes by an enzymatic fluorometric method with an improved deproteinization procedure.
Whole nerve chorda tympani responses to sweeteners in C57BL/6ByJ and 129P3/J mice.
Cloning and expression of a fungal L-arabinitol 4-dehydrogenase gene.
Effect of osmolytes and chaperone-like action of P-protein on folding of nucleocapsid protein of Chandipura virus.
Recombinant Microdochium nivale carbohydrate oxidase and its application in an amperometric glucose sensor.
Gluconobacter oxydans: its biotechnological applications.
Time-dependent modifications of splanchnic circulation in female pigs submitted to end-to-side portacaval anastomosis.
Membrane-bound sugar alcohol dehydrogenase in acetic acid bacteria catalyzes L-ribulose formation and NAD-dependent ribitol dehydrogenase is independent of the oxidative fermentation.
Azospirillum doebereinerae sp. nov., a nitrogen-fixing bacterium associated with the C4-grass Miscanthus.
Isolation and characterization of thermotolerant Gluconobacter strains catalyzing oxidative fermentation at higher temperatures.
High levels of glucose stimulate angiotensinogen gene expression via the P38 mitogen-activated protein kinase pathway in rat kidney proximal tubular cells.
Lactobacillus arizonensis sp. nov., isolated from jojoba meal.
Synthesis of 2',3'-dideoxy-3'-fluoro-L-ribonucleosides as potential antiviral agents from D-sorbitol.
Primary cell cultures of bovine colon epithelium: isolation and cell culture of colonocytes.
Optimized synthesis of L-sorbose by C(5)-dehydrogenation of D-sorbitol with Gluconobacter oxydans.
Investigation of an in vitro model for predicting the effect of food components on calcium availability from meals.
Genetics of L-sorbose transport and metabolism in Lactobacillus casei.
Heterogeneity of pig intestinal D-glucose transport systems.
Hepatic arterial infusion chemotherapy for unresectable confined liver metastases: prediction of systemic toxicity with the application of a scintigraphic and pharmacokinetic approach.
[Unusual coordination behavior of D-fructose towards dimethyltin(IV)2+: metal-promoted deprotonation of alcoholic hydroxyl groups in aqueous solutions at low pH].
Temperature-dependent fermentation of D-sorbitol in Escherichia coli O157:H7.
The effects of polyols on the thermal stability of calf thymus DNA.
Sorbitol removal by the metastatic liver: a predictor of systemic toxicity of intra-arterial chemotherapy in patients with liver metastases.
Prototypal diarrheagenic strains of Hafnia alvei are actually members of the genus Escherichia.
Evaluation of hepatic function in liver cirrhosis: clinical utility of galactose elimination capacity, hepatic clearance of D-sorbitol, and laboratory investigations.
Total and functional hepatic blood flow decrease in parallel with ageing.
Receptor binding activities of Schefflera triterpenoids and oligosaccharides.
Direct fermentation of 2-keto-L-gulonic acid in recombinant Gluconobacter oxydans.
Sugars exert a major influence on the vitrification properties of ethylene glycol-based solutions and have low toxicity to embryos and oocytes.
Synthesis of new N-containing maltooligosaccharides, alpha-amylase inhibitors, and their biological activities.
Prostaglandin E1 infusion and functional hepatic flow in control subjects and in patients with cirrhosis.
Liquid chromatographic determination of sugar alcohols in beverages and foods after nitrobenzoylation.
Hepatic blood flow and splanchnic oxygen consumption in patients with liver failure. Effect of high-volume plasmapheresis.
3-FG as substrate for investigating flux through the polyol pathway in dog lens by 19F-NMR spectroscopy.
Stereoisomers of cyclic urea HIV-1 protease inhibitors: synthesis and binding affinities.
Structural and functional properties of a yeast xylitol dehydrogenase, a Zn2+-containing metalloenzyme similar to medium-chain sorbitol dehydrogenases.
Short-term effects of transjugular intrahepatic portosystemic shunt (TIPS) on functional liver plasma flow in patients with advanced cirrhosis.
Effect of enteral versus parenteral feeding on hepatic blood flow and steady state propofol pharmacokinetics in ICU patients.
Vibrio halioticoli sp. nov., a non-motile alginolytic marine bacterium isolated from the gut of the abalone Haliotis discus hannai.
Roseobacter gallaeciensis sp. nov., a new marine bacterium isolated from rearings and collectors of the scallop Pecten maximus.
Prediction by mathematical simulation of different pathophysiological effects on D-sorbitol bioavailability.
Assessment of the hepatic circulation in humans: new concepts based on evidence derived from a D-sorbitol clearance method.
Arterial-venous shunting in liver cirrhosis.
Hepatic plasma flow estimated according to Fick's principle in patients with hepatic encephalopathy: evaluation of indocyanine green and D-sorbitol as test substances.
A multistep process is responsible for product-induced inactivation of glucose-fructose oxidoreductase from Zymomonas mobilis.
First report of a human isolate of Erwinia persicinus.
Effect of Ca(II), Sr(II), and Ba(II) on the Pulsed Amperometric Detection of Alditols and Carbohydrates at a Gold Electrode in Alkaline Solutions.
Genotypic relationships among strains classified under the (Pasteurella) haemolytica-complex as indicated by ribotyping and multilocus enzyme electrophoresis.
Isolation and some properties of sorbitol oxidase from Streptomyces sp. H-7775.
Environmental and physiological factors affecting the succinate product ratio during carbohydrate fermentation by Actinobacillus sp. 130Z.
Relationships among strains classified with the ruminant Pasteurella haemolytica-complex using quantitative evaluation of phenotypic data.
Pseudoalteromonas antarctica sp. nov., isolated from an Antarctic coastal environment.
Cloning of genes coding for L-sorbose and L-sorbosone dehydrogenases from Gluconobacter oxydans and microbial production of 2-keto-L-gulonate, a precursor of L-ascorbic acid, in a recombinant G. oxydans strain.
Sensitive, selective gas chromatographic-mass spectrometric analysis with trifluoroacetyl derivatives and a stable isotope for studying tissue sorbitol-producing activity.
Inhibition of gluconeogenesis in cultured chicken embryo hepatocytes by Fusarium metabolites.
Determination of functional portal-systemic shunting in patients submitted to hepatic angiography.
Polyol pathway and NADPH-dependent reductases in dog leukocytes.
A simple and rapid method for the determination of D-sorbitol in plasma using the Cobas Mira S.
Identification of Vibrio proteolyticus with a differential medium and a specific probe.
Effect of Saccharides on the Glass-Forming Tendency and Stability of Solutions of 2,3-Butanediol, 1,2-Propanediol, or 1,3-Butanediol in Water, Phosphate-Buffered Saline, Euro-Collins Solution, or Saint Thomas Cardioplegic Solution
Lactitol enhances short-chain fatty acid and gas production by swine cecal microflora to a greater extent when fermenting low rather than high fiber diets.
Plasmodium falciparum: recrudescence of parasites in culture.
Generation mechanism and purification of an inactive form convertible in vivo to the active form of quinoprotein alcohol dehydrogenase in Gluconobacter suboxydans.
Protein-boronic acid conjugates and their binding to low-molecular-mass cis-diols and glycated hemoglobin.
Functional hepatic flow and Doppler-assessed total hepatic flow in control subjects and in patients with cirrhosis.
Biochemical characterization and sequence analysis of the gluconate:NADP 5-oxidoreductase gene from Gluconobacter oxydans.
Association of enterohemolysin and non-fermentation of rhamnose and sucrose with Shiga-like toxin genes in Escherichia coli from calves.
Cloning and nucleotide sequencing of the membrane-bound L-sorbosone dehydrogenase gene of Acetobacter liquefaciens IFO 12258 and its expression in Gluconobacter oxydans.
Prevention of drug absorption in simulated theophylline overdose.
Effects of osmolarity and amino acids in a chemically defined medium on development of rat one-cell embryos.
Aspects of the haemolytic reaction induced by Kanagawa haemolysin of Vibrio parahaemolyticus.
Reduction in toxicity for red blood cells in buffered solutions containing high concentrations of 2,3-butanediol by trehalose, sucrose, sorbitol, or mannitol.
Taxonomic notes: synonymy of Enterobacter cancerogenus (Urosević 1966) Dickey and Zumoff 1988 and Enterobacter taylorae Farmer et al. 1985 and resolution of an ambiguity in the biochemical profile.
Effects of hexoses and their derivatives on glucagon secretion from isolated perfused rat pancreas.
Escherichia coli O157:H7 generates a unique biochemical profile on MicroScan conventional gram-negative identification panels.
19F and 13C NMR studies of polyol metabolism in freeze-tolerant pupae of Hyalophora cecropia.
The importance of NaCl concentration in a chemically defined medium for the development of bovine oocytes matured and fertilized in vitro.
Ontogeny of Na+/D-glucose cotransport in guinea-pig jejunal vesicles: only one system is involved at both 20 degrees C and 35 degrees C.
Rapid determination of functional liver plasma flow in ICU patients by a modified hepatic D-sorbitol plasma clearance method.
Substrate recognition at the binding site in mammalian pancreatic alpha-amylases.
Determination of traces of silicone defoamer in fruit juices by solvent extraction/atomic absorption spectroscopy.
The kinetic mechanism of sheep liver sorbitol dehydrogenase.
Determination of monosaccharides and sugar alcohols in tissues from diabetic rats by high-performance liquid chromatography with pulsed amperometric detection.
Mechanism of D-fructose isomerization by Arthrobacter D-xylose isomerase.
Glucose binding enhances the papain susceptibility of the intracellular loop of the GLUT1 glucose transporter.
Novel NADPH-binding domain revealed by the crystal structure of aldose reductase.
Serological and biochemical properties of Shiga-like toxin (verocytotoxin)-producing strains of Escherichia coli, other than O-group 157, from patients in Germany.
Combined evaluation of total and functional liver plasma flows and intrahepatic shunting.
Trabulsiella guamensis, a new genus and species of the family Enterobacteriaceae that resembles Salmonella subgroups 4 and 5.
D-Xylose (D-glucose) isomerase from Arthrobacter strain N.R.R.L. B3728. Purification and properties.
Aeromonas jandaei (formerly genospecies DNA group 9 A. sobria), a new sucrose-negative species isolated from clinical specimens.
The functioning liver mass.
In vivo metabolism of 3-deoxy-3-fluoro-D-glucose.
Tumor growth-inhibitory glycoprotein secreted from the mouse brain at terminal stage of the ontogeny: molecular homogeneity and requirement of the retained protein conformation for exhibition of the cytotoxic action.
Acrylated phosphonate esters containing 1,3-dioxane and 1,3-dioxolane moieties as adhesion-promoting agents for dentin and hard tissues, I.
Biochemical identification of Aeromonas genospecies isolated from humans.
[The thiobarbituric method for analyzing sugars. III. A method for studying sorbitol dehydrogenase activity].
[The incidence of E. coli O157H7 strains in causing hemorrhagic enterocolitis].
Enterobacter hormaechei, a new species of the family Enterobacteriaceae formerly known as enteric group 75.
Structures of D-xylose isomerase from Arthrobacter strain B3728 containing the inhibitors xylitol and D-sorbitol at 2.5 A and 2.3 A resolution, respectively.
Identification of D-sorbitol 3-phosphate in the normal and diabetic mammalian lens.
Carbohydrate-controlled precipitation of apatite with coprecipitation of organic molecules in human saliva: stabilizing role of polyols.
Pathways for the synthesis of sorbitol from 13C-labeled hexoses, pentose, and glycerol in renal papillary tissue.
[Human infections caused by Enterobacter sakazakii. Microbiologic considerations].
Relationship between mineral metabolism and peroral consumption of sugar alcohols.
Determination of D-sorbitol in human erythrocytes by an improved enzymatic method with fluorometric detection.
D-sorbitol plasma disappearance rate: an index to evaluate changes in liver circulation.
Characterization of Vibrio metschnikovii and Vibrio gazogenes by DNA-DNA hybridization and phenotype.
D-sorbitol clearance.
F-19 MR imaging of glucose metabolism in the rabbit.
Aeromonas schubertii, a new mannitol-negative species found in human clinical specimens.
Fluorine-19 NMR imaging of glucose metabolism.
Short-chain fatty acid production from mono- and disaccharides in a fecal incubation system: implications for colonic fermentation of dietary fiber in humans.
Dental effects of Lycasin in the diet of laboratory rats.
Non-invasive evaluation of portal-systemic shunting in man by D-sorbitol bioavailability.
Hydrolysis of lactitol, maltitol and Palatinit by human intestinal biopsies.
Noninvasive demonstration of in vivo 3-fluoro-3-deoxy-D-glucose metabolism in rat brain by 19F nuclear magnetic resonance spectroscopy: suitable probe for monitoring cerebral aldose reductase activities.
Hepatic clearance of D-sorbitol. Noninvasive test for evaluating functional liver plasma flow.
Aeromonas veronii, a new ornithine decarboxylase-positive species that may cause diarrhea.
Culture Conditions for Production of Thermostable Amylase by Bacillus stearothermophilus.
Re-investigations of selected bovine and ovine strains previously classified as Pasteurella haemolytica and description of some new taxa within the Pasteurella haemolytica-complex.
Enterobacter asburiae sp. nov., a new species found in clinical specimens, and reassignment of Erwinia dissolvens and Erwinia nimipressuralis to the genus Enterobacter as Enterobacter dissolvens comb. nov. and Enterobacter nimipressuralis comb. nov.
Inhibition of in vitro growth of Plasmodium falciparum by a brief exposure to the cationic rhodamine dyes.
Sorbitol clearance: a parameter reflecting liver plasma flow in the rat.
Aggregation of human salivary Ca-proteinates in the presence of simple carbohydrates in vitro.
Photoaffinity labeling of the K562 cell membrane D-glucose transporter with cytochalasin B.
H7 antiserum-sorbitol fermentation medium: a single tube screening medium for detecting Escherichia coli O157:H7 associated with hemorrhagic colitis.
Effect of glucocorticoids on hexose transport in rat adipocytes. Evidence for decreased transporters in the plasma membrane.
Monosaccharide transport into hemocytes of a sipunculan worm Themiste dyscrita.
Leminorella, a new genus of Enterobacteriaceae: identification of Leminorella grimontii sp. nov. and Leminorella richardii sp. nov. found in clinical specimens.
Escherichia fergusonii and Enterobacter taylorae, two new species of Enterobacteriaceae isolated from clinical specimens.
Koserella trabulsii, a new genus and species of Enterobacteriaceae formerly known as Enteric Group 45.
Bacterial reversion assay and micronucleus test carried out on hydrogenated glucose syrups 'Malti-Towa' (powder) and maltitol crystal.
Methane synthesis by membrane vesicles and a cytoplasmic cofactor isolated from Methanobacterium thermoautotrophicum.
Photoaffinity labeling of the stereospecific D-glucose transport system with cytochalasin B.
[Cysteine stability in aqueous amino acid solutions].
Solubility of calcium salts, enamel, and hydroxyapatite in aqueous solutions of simple carbohydrates.
Bioavailability of glucose from Palatinit.
Studies of the extracellular proteolytic activity produced by Propionibacterium acnes.
A simplified method for measuring activity of beta-D-fructofuranoside fructohydrolase (invertase).
Ewingella americana gen.nov., sp.nov., a new Enterobacteriaceae isolated from clinical specimens.
Biochemical characterization of staphylococci isolated from goats.
Escherichia vulneris: a new species of Enterobacteriaceae associated with human wounds.
Adsorbent and cathartic inhibition of enteral drug absorption.
Identification of the stereospecific hexose transporter from starved and fed chicken embryo fibroblasts.
Identification of Vibrio hollisae sp. nov. from patients with diarrhea.
[Changes in the morphology and cytoskeleton of cultured fibroblasts as a result of raised osmotic pressure].
Characterization and Partial Purification of Aldose-6-phosphate Reductase (Alditol-6-Phosphate:NADP 1-Oxidoreductase) from Apple Leaves.
Nutritional significance of fructose and sugar alcohols.
[Inhibition of glucose isomerase from Actinomyces olivocinereus 154 by polyols].
Polyol metabolism by Rhizobium trifolii.
Separation and properties of polyhydric alcohol dehydrogenases from Mycobacterium sp. 279 and Mycobacterium phlei.
Chemotaxis towards sugars by Bacillus subtilis.
Synchronization of Plasmodium falciparum erythrocytic stages in culture.
[Carbon assimilation and taxonomic study of Bacillus subtillis and B. licheniformis].
Characterization and classification of fluorescent pseudomonads isolated from tap water and surface water.
[Coenzyme-induced slow transitions of NADP-sorbitol dehydrogenase from Gluconobacter oxydans].
Histochemical demonstration of glucose-6-phosphate dehydrogenase, D-sorbitol dehydrogenase, and alkaline phosphatase in human ampulla ductus deferentis.
The uptake and overflow of radiolabelled beta-adrenoceptor blocking agents by the isolated vas deferens of the rat.
Polyol permeability of the human red cell. Interpretation of glucose transport in terms of a pore.
[Study of 14 denitrifying soil bacteria of the "pseudomonas stutzeri" group isolated by enrichment culture in the presence of nitrous oxide (author's transl)].
Relationship between the uptake of 3H-(+/-)metaraminol and the density of adrenergic innervation in isolated rat tissues.
Genetic control of soluble NAD-dependent sorbitol dehydrogenase in Drosophila melanogaster.
Sorbistin, a new aminoglycoside antibiotic complex of bacterial origin. III. Structure determination.
Human cytomegalovirus: glycoproteins associated with virions and dense bodies.
Stimulation of the gerbil's gustatory receptors by polyols.
Enzyme activities associated with arabitol and mannitol biosynthesis and catabolism in Schizophyllum commune.
Purification and properties of polyol dehydrogenase from Cephalosporium chrysogenus.
The stereospecificity of sequential nicotinamide-adenine dinucleotide-dependent oxidoreductases in relation to the evolution of metabolic sequences.
Properties of D-xylose isomerase from Streptomyces albus.
Secretion of calcium in pancreatic juice.
Fermentative production of L-sorbose from D-sorbitol by Acetobacter suboxydans (vinegar isolate).
Chemotaxis toward sugars in Escherichia coli.
The effect of tonicity, d-mannitol, d-sorbitol, and choline chloride on the water content of mouse brain slices, and on the compartmentation of the space indicated by 'extracellular space markers'.
The temperature-dependent compartmentation of the 'extracellular space' in mouse brain slices as revealed by the markers: inulin, sucrose, d-mannitol, d-sorbitol and sulfate.
Metabolism of some polyols by Rhizobium meliloti.
THE EFFECTS OF PENICILLIN, DL-PENICILLAMINE, AND D-SORBITOL ON ERYTHROCYTE TRANSKETOLASE ACTIVITY IN THIAMINE-DEFICIENT RATS.
HISTOCHEMICAL STUDY ON THE METABOLISM OF D-SORBITOL IN STARVED RATS.
[Our experiences with D-sorbitol as a contraction meal in peroral cholecystography].
Effect of D-sorbitol on the absorption and transfer of nutrients from mother to fetus.
Parallel induction of D-arabitol and D-sorbitol dehydrogenases.
Oxidation of polyols by Nocardia corallina.
D-Mannitol 1-phosphate dehydrogenase and D-sorbitol 6-phosphate dehydrogenase in Aerobacter aerogenes.
[Experimental analysis of the action of D-sorbitol on phenothiazine-induced intestinal atony].
Dose dependent effects of D-sorbitol on intestinal absorption of vit. B12.
[The combination D-sorbitol-vitamin B 12 in the treatment of anemias].
Effect of feeding D-sorbitol on the intestinal absorption of vitamin B6 and vitamin B12 in rats.
[Recent data on the pharmaceutical applications of D-sorbitol].
D-sorbitol-6-phosphate dehydrogenase from Lactobacillus casei.
Influence of D-sorbitol on absorption of vitamin B12 by patients with pernicious anemia and achlorhydria.
Effect of D-sorbitol on absorption of vitamin B12 by human subjects able to produce intrinsic factor.
Enhancement of serum vitamin B12 by D-sorbitol.
Nutritional supplementation enhanced by D-sorbitol.
Influence of d-Sorbitol on plasma concentrations of vitamin B12.
[Further notes on the pharmaceutical applications of D-sorbitol].
Effect of D-sorbitol on the absorption of orally administered vitamin B12.
Effect of D-sorbitol on absorption of vitamin B12 by pernicious anemia patients.
Studies on the absorption of vitamin B12 in human pregnancy with especial reference to the effect of D-sorbitol.
Enhancement of vitamin B12 absorption of D-sorbitol as measured by maternal and fetal tissue levels in pregnant rats.
Iron absorption and metabolism. III. The enhancement of iron absorption in rats by D-sorbitol.
Absorption of vitamin B12 enhanced by D-sorbitol.
Enhancement of ultraviolet absorption of L-ascorbic acid in the presence of D-sorbitol.
A new synthesis of polygalitol tetraacetate (tetraacetyl-1,5-anhydro-D-sorbitol).

Other Information

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
FDA Indirect Additives used in Food Contact Substances:	View
CHEBI:	View
CHEMBL:	View
Golm Metabolome Database:	Search
Metabolomics Database:	Search
KEGG (GenomeNet):	C00794
HMDB (The Human Metabolome Database):	HMDB00247
FooDB:	FDB011676
YMDB (Yeast Metabolome Database):	YMDB00656
Export Tariff Code:	2905.44.0000
FDA Listing of Food Additive Status:	View
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View
Formulations/Preparations: •sorbitol solution usp is a water solution containing, in each 100 g, 69-71 g of total solids consisting essentially of d-sorbitol and a small amount of mannitol and other isomeric polyhydric alcohols it has been used as replacement for propylene glycol and glycerin. •grades: crystals; technical; 70% aq soln (usp); resin; powder; fcc (solid & soln).

Suppliers

A.M.G.L.T.	Act Polyols
ADM	Allan Chemical
Anhui Haibei	Azelis UK
BBFY Industrial	BOC Sciences
Carbosynth	Cargill, Inc.
ECSA Chemicals	EMD Millipore
Farbest-Tallman Foods	Fleurchem
Glentham Life Sciences	Graham Chemical
H. Interdonati, Inc.	Indis NV
Kao Corporation	Kraft Chemical
Mosselman	Nactis Flavours
Penta International	Prinova
Santa Cruz Biotechnology	Sigma-Aldrich
Silver Fern Chemical	Sinofi Food Ingredients
TCI AMERICA	Tianjin Talent Chemical
United International	Penta International Corporation
Qingdao Free Trade Zone United International Co Ltd

PhysChem Properties

Material listed in food chemical codex	Yes
Molecular weight	182.17277526855
Melting Point	88 to 102°C @ 760 mm Hg
Boiling Point	494 to 495°C @ 760 mm Hg
Flash Point TCC Value	110 °C TCC
logP (o/w)	-3.262 est
Shelf life	48 months (or longer if stored properly.)
Storage notes	Store in cool, dry place in tightly sealed containers, protected from heat and light.
Solubility
water, 2750000 mg/L @ 30 °C (exp)	Yes
alcohol, slightly	Yes

Organoleptic Properties

Odor Type: Caramellic
Odor strength	low
General comment	At 100.00 %. odorless to sweet caramel
Flavor Type: Sweet
sweet, caramellic
General comment	Sweet

Occurrences

Potential Uses

Applications	sweeteners humectants sequestrants texturizers stabilizers bulking agents
Flavoring purposes	Chocolate cocoa
Other purposes	Humectants , Plasticisers , Skin conditioning
Cosmetic purposes	Humectants , Plasticisers , Skin conditioning

Safety Information

Safety information

Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 15900 mg/kg FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 498, 1974. intravenous-rat LD50 7100 mg/kg FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 498, 1974. oral-mouse LD50 17800 mg/kg Yakkyoku. Pharmacy. Vol. 32, Pg. 1367, 1981. intravenous-mouse LD50 9480 mg/kg Yakkyoku. Pharmacy. Vol. 32, Pg. 1367, 1981. intraperitoneal-mouse LD50 15000 mg/kg Proceedings of the Society for Experimental Biology and Medicine. Vol. 35, Pg. 98, 1936.
Dermal Toxicity:
subcutaneous-rat LD50 29600 mg/kg Drugs in Japan Vol. -, Pg. 607, 1990. subcutaneous-mouse LD50 24000 mg/kg Drugs in Japan Vol. -, Pg. 607, 1990.
Inhalation Toxicity:
Not determined

Safety in use information

Category:
sweeteners, humectants, sequestrants, texturizers, stabilizers, bulking agents
Recommendation for dextro-sorbitol usage levels up to:
	not for fragrance use.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
		average usual ppm	average maximum ppm
baked goods:		-	50000.00000
beverages(nonalcoholic):		-	1300.00000
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		-	-
confectionery froastings:		-	500.00000
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	70000.00000
fruit ices:		-	70000.00000
gelatins / puddings:		-	8000.00000
granulated sugar:		-	-
gravies:		-	-
hard candy:		-	21000.00000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	-
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		-	-

Safety references

European Food Safety Authority (EFSA) reference(s):

Outcome of the public consultation on a draft protocol for assessing exposure to sweeteners as part of their safety assessment under the food additives re-evaluation programme
View page or View pdf

EPI System: View

ClinicalTrials.gov:search

Daily Med:search

NIOSH International Chemical Safety Cards:search

Chemical Carcinogenesis Research Information System:Search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA GENetic TOXicology:Search

EPA Substance Registry Services (TSCA):50-70-4

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry