saffron indenone

General Material Information

Preferred name	saffron indenone
Trivial Name	2,3-Dihydro-2,3,3-trimethyl-1H-inden-1-one
Short Description	safraleine (Givaudan)
Formula	C12 H14 O
CAS Number	54440-17-4
FEMA Number	4556
FDA UNII	19D876M98B
xLogP3-AA	3.10 (est)
NMR Predictor	External link
JECFA Food Flavoring	2047 2,3,3-trimethylindan-1-one
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	54440-17-4 ; 2,3,3-TRIMETHYLINDANONE
Synonyms	2,3-dihydro-2,3,3-trimethyl-1H-inden-1-one 1H- inden-1-one, 2,3-dihydro-2,3,3-trimethyl- safraleine (Givaudan) 2,3,3-trimethyl indan-1-one 3,3,2-trimethyl-1-indanone 2,3,3-trimethyl-2,3-dihydro-1H-inden-1-one 2,3,3-trimethyl-2H-inden-1-one 2,3,3-trimethylindan-1-one 2,3,3-trimethylindanone 2,3,3-trimethyl-2H-inden-1-one 1H-Inden-1-one, 2,3-dihydro-2,3,3-trimethyl- 1-Indanone, 2,3,3-trimethyl- 2,3-Dihydro-2,3,3-trimethyl-1H-inden-1-one 2,3,3-Trimethyl-1-indanone 2,3,3-Trimethyl-2,3-dihydro-1H-inden-1-one Safraleine

Publications by Info
Safraleine
Publications by US Patents
7,538,243 - Indanes and indanones and their use in perfumery

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View
FAO:	2,3,3-Trimethylindan-1-one

BOC Sciences	Givaudan
Indukern F&F	Lluch Essence
Moellhausen	Pell Wall Perfumes
Penta International	Perfumery Laboratory
The Perfumers Apprentice	Vigon International
Indukern, S.A. F&F Ingredients Division	Penta International Corporation

Material listed in food chemical codex	No
Molecular weight	174.24278259277
Specific gravity	@ 25 °C
Pounds per Gallon	8.446 to 8.529
Refractive Index	1.532 to 1.542 @ 20 °C
Boiling Point	250 to 252°C @ 760 mm Hg
Vapor Pressure	0.013 mmHg @ 25 °C
Flash Point TCC Value	120 °C TCC
logP (o/w)	3.516 est
Solubility
alcohol	Yes
water, 73.7 mg/L @ 25 °C (est)	Yes
water	No
Stability
alcoholic - good	Unspecified
antiperspirant spray - poor	Unspecified
APC (pH = 10) - good	Unspecified
candles - good	Unspecified
damp fabric - good	Unspecified
dry fabric - good	Unspecified
liquid bleach - poor	Unspecified
pH = 2 - moderate	Unspecified
powder detergent - good	Unspecified
powder detergent + activator - good	Unspecified
soap - good	Unspecified
toiletries - good	Unspecified

Odor Type: Herbal
herbal, leathery, saffron, marine, phenolic, tobacco, woody
Odor strength	high , recommend smelling in a 10.00 % solution or less
Substantivity	168 hour(s) at 10.00 % in dipropylene glycol
Luebke, William tgsc, (2007)	At 10.00 % in dipropylene glycol. herbal leather saffron iodine phenolic tobacco woody
Flavor Type: Herbal
herbal, dry, saffron, tobacco, sage, spicy, phenolic, leathery
Luebke, William tgsc, (2007)	Herbal dry saffron tobacco sage spicy phenolic leathery

Applications	flavor and fragrance agents
Odor purposes	Acacia , Agate , Allspice , Amber , Ambergris , Angelica , Animal , Beeswax absolute replacer , Calamus oil replacer , Cassia , Cassia blossom , Cedar , Cedar forest , Champaca , Chestnut blossom , Chrysanthemum , Chypre , Cigar , Cistus , Clove , Clove blossom , Coronilla , Croton eluteria bark , Dahlia , Deertongue absolute replacer , Dogwood , Fern , Fig , Fir balsam , Fir needle oil replacer , Floral , Flouve , Flouve blossom , Forest , Galangal root , Ginger , Ginger white ginger , Guaiacwood , Gurjun balsam , Hay new mown hay , Herbal , Incense , Iris blossom , Ivy , Jonquil , Juniper , Leather , Lovage root , Musk , Ocean sea , Oriental , Osmanthus , Patchouli , Petunia , Pinion , Redwood , Rose d'orient , Saffron , Sandalwood , Sap , Savin , Soapy sandalwood moss , Spice , Spicewood , Sweet grass , Tobacco , Vanilla , Woodruff , Woody
Flavoring purposes	Angelica , Cistus , Croton eluteria bark , Galangal root , Guaiacwood , Lovage root , Savin
Other purposes	Clean , Diffusion , Dry , Fantasy blends


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 5), H303 Acute toxicity, dermal (Category 5), H313 Skin irritation (Category 2), H315 Acute aquatic toxicity (Category 3), H402 Chronic aquatic toxicity (Category 3), H412
GHS Label elements, including precautionary statements

Pictogram

Signal word	Danger
Hazard statement(s)
H303 - May be harmfulif swallowed H313 - May be harmful in contact with skin H315 - Causes skin irritation H402 - Harmful to aquatic life H412 - Harmful to aquatic life with long lasting effects
Precautionary statement(s)
P264 - Wash skin thouroughly after handling. P273 - Avoid release to the environment. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P302 + P352 - IF ON SKIN: wash with plenty of soap and water. P312 - Call a POISON CENTER or doctor/physician if you feel unwell. P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention. P362 - Take off contaminated clothing and wash before reuse. P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for saffron indenone usage levels up to:
	3.0000 % in the fragrance concentrate.

Structure Class:		I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
		average usual ppm	average maximum ppm
baked goods:		0.00500	0.03000
beverages(nonalcoholic):		0.01000	0.03000
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		0.00500	0.02000
condiments / relishes:		0.01000	0.01000
confectionery froastings:		0.03000	0.05000
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		0.00500	0.02000
fruit ices:		0.01000	0.02000
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		-	-
hard candy:		0.00500	0.01000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		0.03000	0.05000
meat products:		0.30000	5.00000
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		0.00500	0.02000
sugar substitutes:		-	-
sweet sauces:		0.03000	0.05000