phenyl mercuric nitrate

General Material Information

Preferred name	phenyl mercuric nitrate
Trivial Name	(Nitrato-κO)phenylmercury
Short Description	mercury, (nitrato-kappaO)phenyl-
Formula	C6 H5 Hg N O3
CAS Number	55-68-5
ECHA Number	200-242-9
FDA UNII	CG8692ZN14
Beilstein Number	3945322
Bio Activity Summary	External link
NMR Predictor	External link
Synonyms	mercury, (nitrato-kappaO)phenyl- mercury, phenyl-, nitrate nitrooxy(phenyl)mercury phenylmercuric nitrate phenylmercury nitrate Mercury, (nitrato-κO)phenyl- Mercury, nitratophenyl- Mercury, (nitrato-O)phenyl- (Nitrato-κO)phenylmercury Merphenyl nitrate Mersolite 7 Phe-Mer-Nite Phenalco Phenitol Phenmerzyl nitrate Phenylmercurinitrate Nitratophenylmercury Phenylmercury (II) nitrate NSC 4772

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Literature & References

	nitrooxy(phenyl)mercury
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	16682924
Pubchem (sid):	134972284

Publications by PubMed
Temperature-mediated absorption of phenylmercuric nitrate on polyethylene and polypropylene containers in chloramphenicol eye drops.
Antifungal effect of ophthalmic preservatives phenylmercuric nitrate and benzalkonium chloride on ocular pathogenic filamentous fungi.
Eye drops preservative as the cause of corneal band keratopathy in long-term pilocarpine hydrochloride treatment.
Ocular preservatives: associated risks and newer options.
Discovery of potent inhibitors of pseudomonal quorum sensing via pharmacophore modeling and in silico screening.
Oral lichenoid lesions (OLL) and mercury in amalgam fillings.
Patch testing by additional series of allergens: results of further experiences.
Quaternary ammoniums and other preservatives' contribution in oxidative stress and apoptosis on Chang conjunctival cells.
[Epicutaneous sensitization to metals and contact allergic dermatitis: analysis of an ambulatory caseload].
Rapid evaluation of biocidal activity using a transposon-encoded catechol 2,3-dioxygenase from Pseudomonas putida.
Mercurochrome allergy. Immediate and delayed hypersensitivity.
Effect of concentration, pH, and preservative on in vitro transcorneal permeation of ibuprofen and flurbiprofen from non-buffered aqueous drops.
Screening of antiadherent activity on Streptococcus sobrinus culture.
Connubial dermatitis from phenylmercuric nitrate.
Oral lichenoid lesions caused by allergy to mercury in amalgam fillings.
Resistance of adhered bacteria to rigid gas permeable contact lens solutions.
Epidemiology and susceptibilities to mercury preservatives of staphylococci isolated from used eye-drops preserved with thiomersal.
[In vitro changes induced by phenylmercury nitrate on fungi causing keratitis. Scanning electron microscopy study].
Sensitization to thimerosal (Merthiolate) is still present today.
Antibacterial features of lubraseptic jelly.
The decomposition of phenylmercuric nitrate in sulphacetamide drops during heat sterilization.
Determination of phenylmercuric nitrate in pharmaceuticals by HPLC.
The chemical degradation of phenylmercuric nitrate by disodium edetate during heat sterilization at pH values commonly encountered in ophthalmic products.
The decomposition of phenylmercuric nitrate caused by disodium edetate in neomycin eye drops during the process of heat sterilization.
Evaluation of preservatives in eye-drop preparations.
A high-performance liquid chromatographic assay for phenylmercuric nitrate in the presence of zinc ions and its application to an assessment of the stability of phenylmercuric nitrate in zinc sulphate and zinc sulphate and adrenaline eye drops.
Some studies on the preservation of indometacin suspensions intended for ophthalmic use.
High-performance liquid chromatographic investigation of the interaction of phenylmercuric nitrate and sodium metabisulphite in eye drop formulations.
Attempted measurement of the activity of selected preservative combinations.
Interaction between catalytic and regulatory sites of the pyruvate dehydrogenase from Escherichia coli studied by the ESR technique.
Atypical band keratopathy following long-term pilocarpine treatment.
Sustained release ophthalmic formulations of pilocarpine.
The effect of some preservatives used in nasal preparations on mucociliary clearance.
Sensitivity of methicillin-resistant Staphylococcus aureus strains to some antibiotics, antiseptics and disinfectants.
Sporicidal activity of local anaesthetics and their binary combinations with preservatives.
Assay of phenylmercury salts in pharmaceutical products by high-performance liquid chromatography of the morpholinedithiocarbamate derivative.
Comparative susceptibility of hospital isolates of gram-negative bacteria to antiseptics and disinfectants.
Sporicidal activity of local anaesthetics and their binary combinations with preservatives.
Assay of phenylmercuric acetate and nitrate in pharmaceutical products by high-performance liquid chromatography with indirect photometric detection.
[The action of phenylmercuriacetate and nitrate in combined application in rats: the thyroid gland, liver enzymes and morphologic findings in the brain and kidney].
A note on the contamination of eye-drops following use by hospital out-patients.
[The neurotoxicity and mutagenicity of phenylmercury acetate and nitrate in single and combined applications in animal studies].
Antiseptic and antibiotic resistance in gram-negative bacteria causing urinary tract infection in spinal cord injured patients.
Sodium hypophosphite as reducing agent for determination of submicrogram quantities of mercury in animal feeds and manures.
Changes in the abscisic acid content of oat leaves during senescence.
Antiseptic and antibiotic resistance in Gram-negative bacteria causing urinary tract infection.
Determination of phenylmercuric nitrate by potentiometric titration.
Relation between leaf senescence and stomatal closure: Senescence in light.
Survival of plasmid-containing strains of Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus in phenylmercuric nitrate and thiomersal.
Immediate sterility after vasectomy.
A clinical pathologic study of mercurialentis medicamentosus.
Inactivation of Bacillus subtilis spores by heating at 100 degrees with phenylmercuric nitrate or acetate.
Sensitivity of Providence to antiseptics and disinfectants.
Biosynthesis of sulphur amoni acids in Saccharomyces cerevisiae. I. Genetic analysis of leaky mutants of sulphite reductase.
Microbiological determination of drug partitioning. IV. Drug-protein interactions.
Virucidal effect of sodium p-chloromercuribenzoate on influenza viruses attributable to inhibition of virus particle-associated RNA-dependent RNA polymerase.
Purification of monolayer cell cultures of the endocrine pancreas.
Antibacterial activity of phenylmercuric nitrate in zinc sulphate and adrenaline eye drops B.P.C. 1968.
The anactivation of phenylmercuric nitrate by sodium metabisulphite.
Resistance of Bacillus subtilis spores to inactivation by gamma irradiation and heating in the presence of a bactericide. 3. Factors affecting rates of inactivation by phenylmercuric nitrate.
The cathode ray polarography of phenylmercuric nitrate.
[Studies on the absorption of phenyl mercuric nitrate in the stoppers for injection vials].
Properties of a beta-(1-4)-glucan hydrolase from Aspergillus niger.
Mercury sensitivity of staphylococci.
The polarographic characteristics of phenylmercuric nitrate.
The use of antiseptics in the sterilisation of solutions for injection. Part II. The efficiency of phenylmercuric nitrate.
The action of phenylmercuric nitrate; the ability of sulfhydryl compounds to protect against the germicidal action of basic phenylmercuric nitrate.
The Action of Phenylmercuric Nitrate: IV. The Ability of Sulfhydryl Compounds to Protect against the Germicidal Action of Basic Phenylmercuric Nitrate.
The action of phenylmercuric nitrate; the ability of sulfhydryl compounds to protect against the germicidal action of basic phenylmercuric nitrate.
The action of phenylmercuric nitrate; inability of sulfhydryl compounds to reverse the depression of cytochrome oxidase and yeast respiration caused by basic phenylmercuric nitrate.
Phenylmercuric nitrate and related compounds.
The action of phenylmercuric nitrate; sulfhydryl antagonism of respiratory depression caused by phenylmercuric nitrate.
The action of phenylmercuric nitrate; effects on enzyme systems.
Effect of para-aminobenzoic acid and other substances on yeast respiration and on the respiratory-depressant action of phenylmercuric nitrate.
THE PREPARATION AND PROPERTIES OF INFLUENZA VIRUS VACCINES CONCENTRATED AND PURIFIED BY DIFFERENTIAL CENTRIFUGATION.

Other Information

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEMBL:	View
KEGG (GenomeNet):	D05465
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View
Wikipedia:	View

Suppliers

George Uhe Company	Penta International
Penta International Corporation

PhysChem Properties

Material listed in food chemical codex	No
Molecular weight	339.70043945312
Flash Point TCC Value	N/a
Solubility
water, 584.7 mg/L @ 25 °C (est)	Yes

Safety Information

Safety information


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-rabbit LDLo 5 mg/kg JAMA, Journal of the American Medical Association. Vol. 117, Pg. 1784, 1941.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
pharmaceuticals / chemical synthisis
Recommendation for phenyl mercuric nitrate usage levels up to:
	not for fragrance use.

Recommendation for phenyl mercuric nitrate flavor usage levels up to:
	not for flavor use.