1-(2-hydroxy-4-isobutoxyphenyl)-3-(pyridin-2-yl)propan-1-one

General Material Information

Trivial Name	1-(2-hydroxy-4-isobutoxyphenyl)-3-(pyridin-2-yl)propan-1-one
Short Description	1-(2-hydroxy-4-isobutoxyphenyl)-3-(2-pyridyl)propan-1-one
Formula	C18 H21 N O3
CAS Number	1190230-47-7
FEMA Number	4722
FDA UNII	RS9W0RR7AN
xLogP3-AA	4.00 (est)
NMR Predictor	External link
JECFA Food Flavoring	2159 1-(2-hydroxy-4-isobutoxyphenyl)-3-(pyridin-2-yl)propan-1-one
FDA Patent	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm	1190230-47-7 ; 1-(2-HYDROXY-4-ISOBUTOXYPHENYL)-3-(PYRIDIN-2-YL)PROPAN-1-ONE
Synonyms	1-(2-hydroxy-4-isobutoxyphenyl)-3-(2-pyridyl)propan-1-one 1-propanone, 1-[2-hydroxy-4-(2-methylpropoxy)phenyl]-3-(2-pyridinyl)-

	1-(2-hydroxy-4-isobutoxyphenyl)-3-(2-pyridyl)propan-1-one
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	49869550
Pubchem (sid):	342527124

Publications by WIPO Patents
PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR
Publications by Leffingwell & Associates
Flavor Properties of FEMA GRAS List 25 flavor chemicals

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
HMDB (The Human Metabolome Database):	Search
FDA Listing of Food Additive Status:	View
ChemSpider:	View

Material listed in food chemical codex	No
Molecular weight	299.36996459961
Melting Point	47 to 49°C @ 760 mm Hg
Boiling Point	479 to 480°C @ 760 mm Hg
Flash Point TCC Value	243.7 °C TCC
logP (o/w)	4.243 est
Solubility
alcohol	Yes
water, 145.4 mg/L @ 25 °C (est)	Yes
water	No

Odor Type: Savory
General comment	Sweet savory
Flavor Type: Salty
umami, sweet, salty, brothy, bouillon
General comment	At 2.00 ppm in 0.3% salt solution. umami sweet salty brothy bouillon


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
flavoring agents
Recommendation for 1-(2-hydroxy-4-isobutoxyphenyl)-3-(pyridin-2-yl)propan-1-one usage levels up to:
	not for fragrance use.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 25
Click here to view publication 25
		average usual ppm	average maximum ppm
baked goods:		1.00000	2.00000
beverages(nonalcoholic):		-	-
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		2.00000	5.00000
confectionery froastings:		-	-
egg products:		-	-
fats / oils:		-	-
fish products:		2.00000	5.00000
frozen dairy:		-	-
fruit ices:		-	-
gelatins / puddings:		-	-
granulated sugar:		-	-
gravies:		5.00000	30.00000
hard candy:		-	-
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		5.00000	20.00000
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		5.00000	20.00000
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		5.00000	10.00000
snack foods:		5.00000	10.00000
soft candy:		-	-
soups:		5.00000	20.00000
sugar substitutes:		-	-
sweet sauces:		-	-

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :49869550

National Institute of Allergy and Infectious Diseases:Data

1-(2-hydroxy-4-isobutoxyphenyl)-3-(2-pyridyl)propan-1-one

Chemidplus:1190230477