(+)-dehydroisoandrosterone

General Material Information

Preferred name	(+)-dehydroisoandrosterone
Trivial Name	Dehydroepiandrosterone
Short Description	prasterone
Formula	C19 H28 O2
CAS Number	53-43-0
Deleted CAS Number	105597-37-3
ECHA Number	200-175-5
FDA UNII	459AG36T1B
Nikkaji Number	J4.147E
Beilstein Number	2058110
MDL	MFCD00003613
Bio Activity Summary	External link
NMR Predictor	External link
Synonyms	DHEA 17-hormoforin (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one 3b- hydroxy-androst-5-en-17-one 3b- hydroxy-D5-androsten-17-one (3-beta)-3-hydroxyandrost-5-en-17-one (3b)-3-hydroxyandrost-5-en-17-one 3b- hydroxyandrost-5-en-17-one 3b- hydroxyandrost-5-ene-17-one prasterone (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one Androst-5-en-17-one, 3-hydroxy-, (3β)- Androst-5-en-17-one, 3β-hydroxy- (3β)-3-Hydroxyandrost-5-en-17-one 17-Chetovis trans-Dehydroandrosterone Dehydroepiandrosterone Dehydroisoandrosterone DHA 17-Hormoforin 3β-Hydroxyandrost-5-ene-17-one 3β-Hydroxy-Δ5-androsten-17-one 3β-Hydroxyandrost-5-en-17-one Androstenolone Androst-5-ene-3β-ol-17-one 5-Androsten-3β-ol-17-one 5-Dehydroepiandrosterone 5,6-Dehydroisoandrosterone 5,6-Didehydroisoandrosterone Psicosterone Diandron Diandrone Dehydro-epi-androsterone Δ5-Androsten-3β-ol-17-one IM 28 GL 701 Astenile Deandros Siscelar plus NSC 9896 Androst-5-ene-17-one-3β-ol Immunor Intrarosa EM 760 MeSH ID: D003687 (3S,8R,9S,10R,13S,14S)-3-Hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-17H-cyclopenta[a]phenanthren-17-one

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Literature & References

	(3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	53-43-0
Pubchem (cid):	5881
Pubchem (sid):	134971188

Publications by PubMed
Exogenous dehydroisoandrosterone sulfate reverses the dendritic changes of the central neurons in aging male rats.
Positive inotropic activity induced by a dehydroisoandrosterone derivative in isolated rat heart model.
Synthesis of novel ring B Abeo-sterol derivatives and their antiproliferative activities.
Synthesis and in vitro antiproliferative evaluation of some ring B abeo-sterols.
Generation of anti-trenbolone monoclonal antibody and establishment of an indirect competitive enzyme-linked immunosorbent assay for detection of trenbolone in animal tissues, feed and urine.
Neurosteroids modulate compulsive and persistent behavior in rodents: implications for obsessive-compulsive disorder.
Characterization of androgen regulation of ZEB-1 and PSA in 22RV1 prostate cancer cells.
A total synthesis of OSW-1.
Two-dimensional J-spectra with absorption-mode lineshapes.
Enhancement of plasmacytoma cell growth by ascorbic acid is mediated via glucose 6-phosphate dehydrogenase.
Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.
Solid-phase microextraction with on-fiber silylation for simultaneous determinations of endocrine disrupting chemicals and steroid hormones by gas chromatography-mass spectrometry.
OSW saponins: facile synthesis toward a new type of structures with potent antitumor activities.
Synthesis of 26,27-bisnorcastasterone analogs and analysis of conformation-activity relationship for brassinolide-like activity.
Hormonally active nontransformed human ovarian cell culture from oophorectomy specimens: methods of development and initial characterization.
Apolipoprotein A-IV attenuates oxidant-induced apoptosis in mitotic competent, undifferentiated cells by modulating intracellular glutathione redox balance.
A comparison of modulation of proliferation of thymocyte by testosterone, dehydroisoandrosterone and androstenedione in vitro.
Ovariectomy and estradiol replacement therapy alters the adenine nucleotide hydrolysis in rat blood serum.
Inhibition of rat liver sulfotransferases SULT1A1 and SULT2A1 and glucuronosyltransferase by dietary flavonoids.
First Total Synthesis of an Exceptionally Potent Antitumor Saponin, OSW-1.
Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts.
Steroid transformations with Exophiala jeanselmei var. lecanii-corni and Ceratocystis paradoxa.
The metabolic activation of tamoxifen and alpha-hydroxytamoxifen to DNA-binding species in rat hepatocytes proceeds via sulphation.
Identification of the nonsubstrate steroid binding site of rat liver glutathione S-transferase, isozyme 1-1, by the steroid affinity label, 3beta-(iodoacetoxy)dehydroisoandrosterone.
Electron spin echo envelope modulation studies of the semiquinone anion radical of cholesterol oxidase from Brevibacterium sterolicum.
Preliminary study of the metabolism of 17 alpha-methyltestosterone in horses utilizing gas chromatography-mass spectrometric techniques.
Structure-specific inhibition of lysosomal cholesterol transport in macrophages by various steroids.
ESR and electron nuclear double resonance characterization of the cholesterol oxidase from Brevibacterium sterolicum in its semiquinone state.
[Hormonal and biochemical characterization of breast cyst fluid in gross cystic mastopathy].
Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, blocks lysosomal cholesterol trafficking in macrophages.
Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases.
Purification and characterization of 3 beta-hydroxysteroid-dehydrogenase/isomerase from bovine adrenal cortex.
Steroid and cation correlations in human breast cyst fluid: preliminary findings.
Effect of steroids on gamma-aminobutyrate-induced currents in cultured rat astrocytes.
Transport of steroid hormones facilitated by serum proteins.
Steroidal fatty acid esters.
Effects of free fatty acids on the binding of steroid hormones to bovine serum albumin.
Mechanisms of chemoprevention by dietary dehydroisoandrosterone. Inhibition of lymphopoiesis.
Arachidonic acid release from cultured human amnion cells: the effect of dexamethasone.
Dehydroisoandrosterone prevention of autoimmune disease in NZB/W F1 mice: lack of an effect on associated immunological abnormalities.
[Transport of steroid hormones by bovine serum albumin as carrier].
Steroidogenesis in human polycystic ovary.
Testicular steroid metabolism during development in the normal and hypogonadal mouse.
Liver composition and lipid metabolism in NZB/W F1 female mice fed dehydroisoandrosterone.
Substrate specificity for formation of cholesterol ester conjugates from fenvalerate analogues and for granuloma formation.
Origin of deoxycorticosterone and deoxycorticosterone sulfate in human pregnancy: absence of steroid 21-sulfatase activity in sulfatase-deficient placenta.
In situ steroid sulfatase activity in human epithelial carcinoma cells of vaginal, ovarian, and endometrial origin.
Control of circadian and episodic variations of adrenal androgens secretion in man.
Stimulation of glycogen phosphorylase kinase by phospholipids.
Metabolism of dehydroisoandrosterone and androstenedione by human A-549 alveolar type II epithelial-like cells.
Steroid sulfatase activity in amnion tissue and amnion cells maintained in monolayer culture.
Prevention of autoantibody formation and prolonged survival in New Zealand black/New Zealand white F1 mice fed dehydroisoandrosterone.
The assay and partial characterization of 3 beta-hydroxysteroid sulfotransferase of the hamster epididymis.
Distribution of steroid sulfotransferase in the male hamster reproductive tract.
Umbilical cord plasma concentrations of deoxycorticosterone sulfate in anencephalic fetuses.
Steroid sulfatase and 17 beta-hydroxysteroid oxidoreductase activities in mouse tissues.
The effect of hypertension in pregnant women on fetal adrenal function and fetal plasma lipoprotein-cholesterol metabolism.
Estriol in human breast cyst fluid.
Steroid sulfatase activity in human lung tissue and in endothelial pulmonary cells in culture.
Steroidogenesis in dispersed cells of human fetal adrenal.
Metabolism of dehydroisoandrosterone and androstenedione in human pulmonary endothelial cells in culture.
Subnormal plasma dehydroisoandrosterone to cortisol ratio in anorexia nervosa: a second hormonal parameter of ontogenic regression.
[Intravenous glucose tolerance test in the polycystic ovary syndrome].
Abnormal levels of plasma hormones in men with prostate cancer: evidence toward a "two-disease" theory.
Abnormal hormone levels in men with coronary artery disease.
Lipoidal derivative of estradiol: the biosynthesis of a nonpolar estrogen metabolite.
Abnormal 24-hr mean plasma concentrations of dehydroisoandrosterone and dehydroisoandrosterone sulfate in women with primary operable breast cancer.
The role of cyclic adenosine 3',5'-monophosphate in cholesterol metabolism and steroidogenesis by the human fetal adrenal gland.
[In Process Citation].
Failure to detect delta 5-3 beta-hydroxysteroid oxidoreductase activity in the preimplantation rabbit embryo.
Steroid hormone accumulation in human breast cyst fluid.
Metabolism of high density lipoprotein by human fetal adrenal tissue.
Steroid secretion by ACTH-stimulated human fetal adrenal tissue during the first week in organ culture.
Subnormal plasma adrenal androgen levels in men with uremia.
Sex difference in the metabolism of dehydroisoandrosterone sulfate.
Sex differences in the twenty-four-hour mean plasma concentrations of dehydroisoandrosterone (DHA) and dehydroisoandrosterone sulfate (DHAS) and the DHA to DHAS ratio in normal adults.
Biosynthesis of lipoidal derivatives of pregnenolone and dehydroisoandrosterone by the adrenal.
Inverse relation between low-density lipoprotein-cholesterol and dehydroisoandrosterone sulfate in human fetal plasma.
Regulation of steroid secretion by adrenal tissue of a human anencephalic fetus.
The lipoidal derivatives of steroids as biosynthetic intermediates.
Relationship of maternal placental blood flow to the placental clearance of maternal plasma dehydroisoandrosterone sulfate through placental estradiol formation.
C19 steroidal precursors of estrogens.
The role of serum lipoproteins in steroidogenesis by the human fetal adrenal cortex.
Plasma testosterone levels before and after stimulation with HCG in anorchism.
Dehydroisoandrosterone sulfate in peripheral blood of premenopausal, pregnant and postmenopausal women and men.
Study of the kinetics of conversion of maternal plasma dehydroisoandrosterone sulfate to 16 alpha-hydroxydehydroisoandrosterone sulfate, estradiol, and estriol.
The effect of oral contraceptive treatment on the serum concentration of dehydroisoandrosterone sulfate.
Urinary 5 alpha-androstane-3 alpha,17 beta-diol radioimmunoassay: a new clinical evaluation.
Solubilization and partial purification of steroid sulfatase of human placenta.
The effect of systemic infusions of dehydroisoandrosterone on the distribution of uterine blood flow in ovine pregnancy.
Method for screening urinary steroids by gas chromatography.
Fetal considerations. Metabolic clearance rate of maternal plasma dehydroisoandrosterone sulfate.
Relationship of the metabolic clearance rate of dehydroisoandrosterone sulfate to placental blood flow.
The effect of flutamide on testosterone metabolism and the plasma levels of androgens and gonadotropins.
Uteroplacental blood flow and estrogen production following dehydroisoandrosterone infusion.
Massive extranglandular aromatization of plasma androstenedione resulting in feminization of a prepubertal boy.
Metabolic clearance of dehydroisoandrosterone.
The metabolism and 24-hour plasma concentrations of androsterone in man.
Metabolism of dehydroisoandrosterone and androstenedione by the human lung in vitro.
5-ene-3beta-hydroxysteroid dehydrogenase of human and bovine adrenocortical endoplasmic reticulum: solubilization and fractionation.
Purification and characterization of N-hydroxy-2-acetylaminofluorene sulfotransferase from rat liver.
Biosynthesis of steroid sulfates by the boar testes.
The pattern and rates of metabolism of maternal plasma dehydroisoandrosterone sulfate in human pregnancy.
Relationship of the metabolic clearance rate of dehydroisoandrosterone sulfate to placental blood flow: a mathematical model.
Metabolic clearance rate of dehydroisoandrosterone sulfate. VII. Effect of lateral versus supine recumbency.
Metabolic clearance rate of dehydroisoandrosterone sulfate. VI. Studies of eclampsia.
Metabolic clearance rate of dehydroisoandrosterone sulfate. V. Studies of essential hypertension complicating pregnancy.
The metabolic clearance rate of dehydroisoandrosterone sulfate. IV. Acute effects of induced hypertension, hypotension, and naturesis in normal and hypertensive pregnancies.
[Adrenocortical function in myasthenia pseudoparalytica].
Plasma precursors of estrogen. III. Conversion of plasma dehydroisoandrosterone to estrogen in young nonpregnant women.
The metabolic clearance rate of dehydroisoandrosterone sulfate. III. The effect of thiazide diuretics in normal and future pre-eclamptic pregnancies.
Direct analysis of dehydroisoandrosterone in plasma.
24-Hour secretory pattern of dehydroisoandrosterone and dehydroisoandrosterone sulfate.
Formation of steroids by the pregnant mare. V. Metabolism of 14C-isopentenylpyrophosphate and 3H-dehydroisoandrosterone injected into the fetus.
[Effect of almagel on the urinary excretion of neutral 17-ketosteroids, dehydroisoandrosterone and free catecholamines in peptic ulcer].
Preparation and antigenic properties of androsterone-7-BSA conjugate.
[Proceedings: Effects of metopirone on plasma androgens variations in women (author's transl)].
Stimulation of 16alpha-hydroxylation of dehydroisoandrosterone sulfate by diethylstilbestrol.
Formation of steroids by the pregnant mare. IV. Metabolism of 14 C-mevalonic acid and 3 H-dehydroisoandrosterone injected into the fetal circulation.
Formation of steroids by the pregnant mare. 3. Metabolism of 14C-squalene and 3H-dehydroisoandrosterone injected into the fetal circulation.
Studies in porphyria. I. A defect in the reductive transformation of natural steroid hormones in the hereditary liver disease, acute intermittent porphyria.
Metabolism and interconversion of dehydroisoandrosterone and dehydroisoandrosterone sulfate.
Study of the metabolic clearance rate of dehydroisoandrosterone sulfate in pregnancy.
Dehydroisoandrosterone is secreted episodically and synchronously with cortisol by normal man.
Behaviour of dehydroisoandrosterone, testosterone and their conjugates on DEAE-Sephadex.
Metabolism of dehydroisoandrosterone and other steroids by surviving slices of the potato tuber and additional plant tissues.
Percentage of testosterone, androstenedione, and dehydroisoandrosterone bound to plasma protein in preadolescent children.
Formation of estrogens by the pregnant mare. I. Metabolism of 7-3H-dehydroisoandrosterone and 4-14C-androstenedione injected into the umbilical vein.
[A method for the determination of dehydroisoandrosterone].
Measurement of solvolyzable esters of androsterone and dehydroisoandrosterone in human plasma.
The in vitro utulization of (4-14C)-dehydroisoandrosterone by human adrenocortical tumors associated with virilism.
[Various aspects of steroidogenesis in congenital adrenogenital syndrome with or without salt loss (determination of the urinary excretion of aldosterone, androsterone, etiocholanolone, dehydroisoandrosterone, 17-hydroxy-11-desoxycorticosterone, pregnanediol and pregnanetriol)].
Sebaceous gland response in man to the administration of testosterone, delta-4-androstenedione, and dehydroisoandrosterone.
[The urinary 11-desoxy-17-ketosteroids (androsterone, etiocholanolone, dehydroisoandrosterone) in childhood. Gas chromatographic study].
[Application of Pettenkofer reaction for determination of dehydroisoandrosterone in 11-desoxy-17-ketosteroid fraction].
Percentage binding of testosterone, androstenedione and dehydroisoandrosterone in human plasma.
Comparisons of the dehydroisoandrosterone-delta-5-3-beta-hydroxysteroid dehydrogenase and the delta-5-pregnenolone-delta-5-3-beta-hydroxysteroid dehydrogenase activities of ovaries of control, hemiovariectomized, gonadotrophin-treated and "androgen-sterilized" young rats.
Testosterone-binding globulins in human plasma: studies on sex distribution and specificity.
[Study of some aspects of gonado-adrenal function in children during the third stage of childhood. Gas-chromatographic evaluation of urinary 11-deoxy-17-ketosteroids (androsterone, etiocholanolone, dehydroisoandrosterone)].
Metabolism of dehydroisoandrosterone-4-14C, 4beta-3H in man.
Metabolism of dehydroisoandrosterone glucuronide.
[Cytohormonal pictures of vaginal smears in women with elevated values of dehydroisoandrosterone in urine].
[Gaschromatographic evaluation of urinary 11-deoxy-17-ketosteroids (androsterone, etiocholanonone, dehydroisoandrosterone) in subjects in the 3d stage of childhood].
[Remarks on the behavior of the lipoproteic pattern and of hematic coagulation after administration of dehydroisoandrosterone].
Microbiological 16-alpha-hydroxylation of dehydroisoandrosterone-3-sulfate.
In vivo conversion of dehydroisoandrosterone to plasma androstenedione and testosterone in man.
Biosynthetic studies of human ovarian arrhenoblastomatous tissue in vitro. II. Formation of androgens from dehydroisoandrosterone sulfate.
Fate of injected dehydroisoandrosterone, testosterone, and dehydroiisoandrosterone sulfate in plasma in the human.
Metabolism of 7-3H-dehydroisoandrosterone in patients with virilizing adrenal tumors.
[Clinical trial of dehydroisoandrosterone for terminal cases of malignant tumors].
THE BINDING OF ANDROSTERONE SULFATE, ETHIOCHOLANOLONE SULFATE, AND DEHYDROISOANDROSTERONE SULFATE BY HUMAN PLASMA PROTEIN.
SIGNIFICANCE OF PLASMA DEHYDROISOANDROSTERONE AND ANDROSTERONE SULFATES IN THE DIAGNOSIS OF VIRILIZING DISORDERS.
SYNTHESIS OF PREGNENOLONE SULFATE, DEHYDROISOANDROSTERONE SULFATE, 17-ALPHA-HYDROXYPREGNENOLONE SULFATE AND DELTA-5-PREGNENETRIOL SULFATE BY THE NORMAL HUMAN ADRENAL GLAND.
AN ADRENAL-SECRETED "ANDROGEN": DEHYDROISOANDROSTERONE SULFATE. ITS METABOLISM AND A TENTATIVE GENERALIZATION ON THE METABOLISM OF OTHER STEROID CONJUGATES IN MAN.
QUANTITATIVE STUDIES ON THE METABOLISM OF DEHYDROISOANDROSTERONE SULFATE.
BIOSYNTHESIS OF ESTROGENS IN PREGNANCY: PRECURSOR ROLE OF PLASMA DEHYDROISOANDROSTERONE.
[4-CHLOROSTEROIDS. SYNTHESIS OF 4-BETA-CHLORO-DEHYDROISOANDROSTERONE ACETATE AND OF 4-CHLORO-4-ANDROSTEN-3 BETA-OL-17-ONE ACETATE].
CONVERSION OF H3-DEHYDROISOANDROSTERONE (3BETA-HYDROXY-DELTA5-ANDROSTEN-17-ONE) SULFATE TO H3-ESTROGENS IN NORMAL PREGNANT WOMEN.
EVIDENCE THAT STEROID SULFATES SERVE AS BIOSYNTHETIC INTERMEDIATES: IN VIVO CONVERSION OF PREGNENOLONE-SULFATE-S35 TO DEHYDROISOANDROSTERONE SULFATE-S35.
Occurrence of dehydroisoandrosterone glucuronoside in normal human urine.
Effect of dehydroisoandrosterone on the in vivo conversion of 17Alpha-hydroxypregnenolone to urinary 11-desoxy-17-ketosteroids.
Biosynthesis of dehydroisoandrosterone sulfate by human adrenocortical tissue.
Precursors of the urinary 11-desoxy-17-ketosteroids: estimation of the secretory rate of dehydroisoandrosterone.
Dehydroisoandrosterone synthesis by the human ovary.
[Substance H3 and dehydroisoandrosterone in psychiatry].
[Attempted synthesis of testosterone from dehydroisoandrosterone by microbiological means].
[Nidation induced by small doses of dehydroisoandrosterone in the female rat].
[Data on the therapeutic association of nialamide and dehydroisoandrosterone in mental disorders of the female climacteric].
[Steroid conjugates. VII. Excretion of dehydroisoandrosterone sulfate and androsterone sulfate in human urine].
The conversion in vivo of dehydroisoandrosterone sulfate to androsterone and etiocholanolone glucuronidates.
[Association of long-acting procaine and dehydroisoandrosterone in the geriatric psychophysical revitalizing treatment. Preliminary report].
[Metabolism of dehydroisoandrosterone in the dog's liver].
[Geriatric therapeutic trial of an injectable combination of procaine and dehydroisoandrosterone].
[Combination of an insoluble procaine salt and dehydroisoandrosterone in the treatment of arteriosclerosis and post-thrombotic cerebral syndrome].
The conversion in vivo of 17-alpha-hydroxypregnenolone to dehydroisoandrosterone and other 17-ketosteroids.
[Observations on the effects of the androgenic steroid hormone dehydroisoandrosterone in white rats].
[Effects of dehydroisoandrosterone in clinical medicine and in therapy; modification of renal function examined by clearance test and of blood sodium, potassium and chlorine].
[Hypersecretion of dehydroisoandrosterone and related compounds in males with symptoms of intersexuality].
[Semiological significance of simultaneous determination of urinary dehydroisoandrosterone for the accurate physiopathological interpretation of urinary 17-ketosteroid values in hypogonadal subjects].
[Metabolism of dehydroisoandrosterone in women with so-called idiopathic hypertrichosis].
[Use of dehydroisoandrosterone in the treatment of colitis].
[Dehydroisoandrosterone in clinical practice].
[Biosynthesis of ovarian steroids; urinary elimination of phenolic steroids after testosterone and dehydroisoandrosterone load].
[Further observations on the dehydroisoandrosterone load test; urinary pregnandiol].
Excretion post-operatively of 17-ketosteroids and dehydroisoandrosterone.
[Dehydroisoandrosterone in mental diseases].
[Clinical aspects of orally administered dehydroisoandrosterone].
The excretion of total neutral 17-ketosteroids and of dehydroisoandrosterone postoperatively.
[Urinary elimination of 17-ketosteroids and dehydroisoandrosterone in patients with various endocrine diseases (Addison's disease, Cushing's disease, Cushing's syndrome, precocious puberty caused by congenital adrenal hyperplasia, acromegaly)].
Use of dehydroisoandrosterone in psychiatric practice.
[Effects of dehydroisoandrosterone on carbohydrate and cholesterol metabolism].
[Use of dehydroisoandrosterone in pilots affected with flying fatigue].
[Urinary elimination of 17-ketosteroids and dehydroisoandrosterone in normal adult individuals of both sexes].
[Urinary elimination of 17-ketosteroids and dehydroisoandrosterone in patients with so-called idiopathic hypertrichosis].
Identification and isolation of dehydroisoandrosterone from peripheral human plasma.
[Urinary elimination of 17-ketosteroids and dehydroisoandrosterone in patients with various chronic diseases or patients with surgical trauma].
[Activity of adrenal cortex during radium therapy; determination of dehydroisoandrosterone].
Metabolic precursors of urinary dehydroisoandrosterone.
[Use of dehydroisoandrosterone in psychiatry].
[Determination of 17-ketosteroids measured in dehydroisoandrosterone units in menstruation disorders].
[Preliminary findings on the use of dehydroisoandrosterone in psychiatric diseases].
[First clinical results of application of dehydroisoandrosterone in the neuropsychiatric field].
[Dehydroisoandrosterone, the Allen reaction and the relative absorption spectrum curves in diagnosis of tumors of the adrenal cortex; observations in 7 cases of hypercorticalism].
[Effect of dehydroisoandrosterone acetate on neoplastic formation in Lebistes reticulatus Pet].
The excretion of dehydroisoandrosterone and some of its derivatives by healthy subjects.
Treatment of inadequate personality in juveniles by dehydroisoandrosterone; preliminary report.
Use of dehydroisoandrosterone in psychiatric treatment; a preliminary survey.
The excretion of dehydroisoandrosterone during adrenal stimulation with adrenocorticotropic hormone.
Urinary dehydroisoandrosterone in hyperadrenocorticism: influence of cortisone, hydrocortisone and ACTH.
Determination of dehydroisoandrosterone and 17-ketosteroids.
Urinary neutral 17-ketosteroids in psoriasis; with special reference to the dehydroisoandrosterone and closely related steroids and excretory changes during fever- and ACTH-therapy.
[Diagnosis of virilizing tumors of the adrenal cortex: effect of cortisone on urinary steroids and application of a calorimetric method for determination of dehydroisoandrosterone].
The determination of urinary dehydroisoandrosterone in normal men and women and in adrenal disease.
The effect of adrenal stimulation with adrenocorticotrophic hormone on the excretion of dehydroisoandrosterone in man.
Hamburger's "micro" method for neutral 17-ketosteroids. The recovery of dehydroisoandrosterone acetate added to water and urine.
Pteroylglutamic acid-like effect of dehydroisoandrosterone on growth of certain microorganisms.
The significance of urinary dehydroisoandrosterone.
Quantitative determination of dehydroisoandrosterone; determination in pure solutions.
Metabolism of the steroid hormones; metabolism of dehydroisoandrosterone.
A modified Pettenkofer reaction for the quantitative estimation of dehydroisoandrosterone and its application to analysis of urinary extracts and fractionations.
Metabolism of dehydroisoandrosterone in a woman before and after removal of an adrenocortical tumor.
Regulation of urinary steroid excretion; effects of dehydroisoandrosterone and of anterior pituitary extract on the pattern of daily excretion in man.
Regulation of urinary steroid excretion. 1. Effects of dehydroisoandrosterone and of anterior pituitary extract on the pattern of daily excretion in man.
16-C13-dehydroisoandrosterone acetate.
A colorimetric method for estimation of dehydroisoandrosterone and its application to urine extracts.
Dimercaptols of dehydroisoandrosterone.
Specificity of a colorimetric method for dehydroisoandrosterone in urine extracts.
The estimation of dehydroisoandrosterone and related compounds in human urine by a modification of the Pettenkoffer reaction.
Substances isolated following the incubation of dehydroisoandrosterone, androsterone and etiocholanolone with liver tissue.
The influence of mixtures of androsterone and dehydroisoandrosterone on biological response.
Studies on intermediary steroid metabolism; isolation of delta-androstene-3(beta), 17(alpha)-diol and delta5-androstene-3(beta), 16(beta), 17(alpha)-triol following the incubation of dehydroisoandrosterone with surviving rabbit liver slices.
Urinary steroids isolated after administration of dehydroisoandrosterone to human subjects.
Steroids; the preparation of androstan-3 beta-ol-7-one from dehydroisoandrosterone.
Metabolism of dehydroisoandrosterone.
Metabolism of dehydroisoandrosterone.

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PhysChem Properties

Material listed in food chemical codex	No
Molecular weight	288.43057250977
Flash Point TCC Value	182.1 °C TCC
logP (o/w)	3.23
Solubility
water, 63.5 mg/L @ 25 °C (exp)	Yes
water, 80.88 mg/L @ 25 °C (est)	Yes

Safety Information

Safety information

Preferred SDS: View

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-man TDLo 10 mg/kg/2W-I CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) Annals of Internal Medicine. Vol. 129, Pg. 588, 1998. oral-mouse LD50 > 10000 mg/kg British UK Patent Application. Vol. #2208473 oral-rat LD50 > 10000 mg/kg British UK Patent Application. Vol. #2208473
Dermal Toxicity:
subcutaneous-mouse LD50 900 mg/kg British UK Patent Application. Vol. #2208473 subcutaneous-rat LD50 1000 mg/kg British UK Patent Application. Vol. #2208473
Inhalation Toxicity:
Not determined

Safety in use information

Category:
pharmaceuticals / chemical synthisis
Recommendation for (+)-dehydroisoandrosterone usage levels up to:
	not for fragrance use.

Recommendation for (+)-dehydroisoandrosterone flavor usage levels up to:
	not for flavor use.

Safety references

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EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :5881

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:2

(3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one

Chemidplus:0000053430

RTECS:BV8396000 for cas# 53-43-0