(1S,2R,5R)-(+)-isomenthol

General Material Information

Preferred name	(1S,2R,5R)-(+)-isomenthol
Trivial Name	(+)-Isomenthol
Short Description	cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1S,2R,5R)-
Formula	C10 H20 O
CAS Number	23283-97-8
ECHA Number	245-554-6
FDA UNII	RCZ2YJZ08S
Nikkaji Number	J208.635B
Beilstein Number	1902291
MDL	MFCD00062984
xLogP3-AA	3.00 (est)
Bio Activity Summary	External link
NMR Predictor	External link
Synonyms	cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1S,2R,5R)- menthol, trans-1,3,cis-1,4-, (+)- (1S,2R,5R)-5-methyl-2-propan-2-ylcyclohexan-1-ol (1S,2R,5R)-2-iso propyl-5-methylcyclohexanol (1S,2R,5R)-5-methyl-2-propan-2-ylcyclohexan-1-ol Menthol, (1R,3S,4R)-(+)- Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1S-(1α,2β,5β)]- (1S,2R,5R)-5-Methyl-2-(1-methylethyl)cyclohexanol (+)-Isomenthol d-Isomenthol

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEMBL:	View
HMDB (The Human Metabolome Database):	Search
Export Tariff Code:	2906.19.0000
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View
Formulations/Preparations: •some synthetic menthols are not chemical individuals but...mixtures of various isomers...these are designated...l-menthol, dl-menthol, l-isomenthol, d-isomenthol, dl-isomenthol, l-neomenthol, d-neomenthol, l-neoisomenthol, d-neoisomenthol and dl-neoisomenthol. •when mixed with about equal wt of camphor, chloral hydrate, phenol, or thymol, menthol forms "eutectic" mixt liquifying @ room temp. •menthol, usp drug marketed under generic name. •grades: technical; usp; fcc •synthetic menthol is available as the optically active levo-menthol with a purity of 99.9%. synthetic menthol is also commercially available as the racemic mixture •present in cigarettes and pipe tobacco (0.1-0.45%) shaving creams, pre- and aftershave lotions (0.2-0.3%); toothpastes (0.5%); mouthwashes (1-2%); chewing gums (0.5%); cough drops (0.1%); refreshing towels (1%); rubbing alcohol (1-1.2%); and shampoos (2-0.5%) •mentholatum deep heating rub contains 5.9% menthol; mentholatum ointment, 1.35%; mentholatum deep heating lotion, 6%

BOC Sciences	ExtraSynthese
Glentham Life Sciences	Sigma-Aldrich

Material listed in food chemical codex	No
Molecular weight	156.26860046387
Melting Point	79 to 80°C @ 760 mm Hg
Vapor Pressure	0.032 mmHg @ 25 °C
Flash Point TCC Value	93.3 °C TCC
logP (o/w)	3.19
Solubility
alcohol	Yes
water, 434.5 mg/L @ 25 °C (est)	Yes
water	No

Odor Type: Musty
musty, sweet, herbal, earthy, camphoreous, hay
General comment	At 10.00 % in dipropylene glycol. musty sweet herbal earthy camphor hay


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Category:
natural substances and extractives
Recommendation for (1S,2R,5R)-(+)-isomenthol usage levels up to:
	not for fragrance use.

Recommendation for (1S,2R,5R)-(+)-isomenthol flavor usage levels up to:
	not for flavor use.

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Toxicology Citations:Search

EPA Substance Registry Services (TSCA):23283-97-8

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :45056

National Institute of Allergy and Infectious Diseases:Data

(1S,2R,5R)-5-methyl-2-propan-2-ylcyclohexan-1-ol

Chemidplus:0023283978