2-benzyl pyridine

General Material Information

Preferred name	2-benzyl pyridine
Trivial Name	2-(Phenylmethyl)pyridine
Short Description	pyridine, 2-(phenylmethyl)-
Formula	C12 H11 N
CAS Number	101-82-6
ECHA Number	202-979-1
FDA UNII	EW2N4V60MQ
Nikkaji Number	J36.122D
Beilstein Number	0115875
MDL	MFCD00006352
xLogP3-AA	2.80 (est)
Bio Activity Summary	External link
NMR Predictor	External link
Synonyms	2-benzylpyridine 2-( phenylmethyl)pyridine pyridine, 2-(phenylmethyl)- pyridine, 2-benzyl- 2-benzylpyridine 2-(Phenylmethyl)pyridine CDD 3529 NSC 241072 NSC 4033

Publications by US Patents
3,931,166 - Certain 2,5-dimethyl-3-thiopyrazines
Flavoring agent
Publications by PubMed
Spectroscopic (FTIR, FT-Raman, UV and NMR) investigation and NLO, HOMO-LUMO, NBO analysis of 2-Benzylpyridine based on quantum chemical calculations.
Copper-catalyzed α-methylenation of benzylpyridines using dimethylacetamide as one-carbon source.
Ruthenium(II) complexes of 2-benzoylpyridine-derived thiosemicarbazones with cytotoxic activity against human tumor cell lines.
Interaction between tetramethylcucurbit[6]uril and some pyridine derivates.
Synthesis, characterization, and preliminary oxygenation studies of benzyl- and ethyl-substituted pyridine ligands of carboxylate-rich diiron(II) complexes.
Oxidation of sulfide, phosphine, and benzyl substrates tethered to N-donor pyridine ligands in carboxylate-bridged diiron(II) complexes.
Reactions of an amphoteric terminal tungsten methylidyne complex.
Induction of hepatic microsomal cytochrome P450 and drug-metabolizing enzymes by 4-benzylpyridine and its structurally related compounds in rats. Dose- and sex-related differential induction of cytochrome P450 species.
Drug metabolizing enzyme induction by simple diaryl pyridines; 2-substituted isomers selectively increase only conjugation enzyme activities, 4-substituted isomers also induce cytochrome P450.
alpha-(2-Pyridine)benzyl aryl ketones as potential hypocholesteremic agents.

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEMBL:	View
HMDB (The Human Metabolome Database):	Search
Export Tariff Code:	2933.39.9100
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View

EMD Millipore	Penta International
Santa Cruz Biotechnology	Sigma-Aldrich: Aldrich
TCI AMERICA	Penta International Corporation

Material listed in food chemical codex	No
Molecular weight	169.22666931152
Specific gravity	@ 20 °C
Pounds per Gallon	8.781 to 8.822
Refractive Index	1.576 to 1.582 @ 20 °C
Boiling Point	266 to 267°C @ 760 mm Hg
Vapor Pressure	0.008 mmHg @ 25 °C
Flash Point TCC Value	125 °C TCC
logP (o/w)	2.57 est
Solubility
alcohol	Yes
water, 3017 mg/L @ 25 °C (est)	Yes
water	No

Preferred SDS: View

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
subcutaneous-mouse LD50 1500 mg/kg BEHAVIORAL: TREMOR CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 227, Pg. 129, 1955.
Inhalation Toxicity:
Not determined

Category:
natural substances and extractives
Recommendation for 2-benzyl pyridine usage levels up to:
	not for fragrance use.

Recommendation for 2-benzyl pyridine flavor usage levels up to:
	not for flavor use.

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):101-82-6

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :7581

National Institute of Allergy and Infectious Diseases:Data

2-benzylpyridine

Chemidplus:0000101826

RTECS:US2620000 for cas# 101-82-6