gamma-damascone

General Material Information

Preferred name	gamma-damascone
Trivial Name	1-(2,2-Dimethyl-6-methylenecyclohexyl)-2-buten-1-one
Formula	C13 H20 O
CAS Number	35087-49-1
FDA UNII	Search
Nikkaji Number	J2.513.699C
xLogP3-AA	3.50 (est)
NMR Predictor	External link
Synonyms	damascone gamma 1-(2,2-dimethyl-6-methylene cyclohexyl)-2-buten-1-one (E)-1-(2,2-dimethyl-6-methylidenecyclohexyl)but-2-en-1-one (E)-1-(2,2-dimethyl-6-methylidenecyclohexyl)but-2-en-1-one 2-Buten-1-one, 1-(2,2-dimethyl-6-methylenecyclohexyl)- 1-(2,2-Dimethyl-6-methylenecyclohexyl)-2-buten-1-one γ-Damascone

US / EU / FDA / JECFA / FEMA / Scholar / Patents

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Perfumer & Flavorists	Start search
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NCBI	Start search

Literature & References

Leffingwell:	Chirality or Article
	(E)-1-(2,2-dimethyl-6-methylidenecyclohexyl)but-2-en-1-one
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	35087-49-1
Pubchem (cid):	9837013
Pubchem (sid):	135265260

Publications by US Patents
3,975,310 - Cycloaliphatic unsaturated ketones as odor- and taste-modifying agents

Other Information

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View

Suppliers

Azelis UK	Ernesto Ventós
Firmenich	M&U International
Penta International	Vigon International
M&U International LLC	Penta International Corporation
Ernesto Ventós S.A.

PhysChem Properties

Material listed in food chemical codex	No
Molecular weight	192.30160522461
Specific gravity	@ 20 °C
Pounds per Gallon	7.731 to 7.781
Refractive Index	1.493 to 1.497 @ 20 °C
Acid Value	1 max KOH/g
Vapor Pressure	0.008 mmHg @ 25 °C
Vapor Density	6.7
Flash Point TCC Value	97.78 °C TCC
logP (o/w)	3.4
Solubility
alcohol	Yes
water, 8.831 mg/L @ 25 °C (est)	Yes
water	No

Organoleptic Properties

Odor Type: Floral
fruity, floral, rose, green, apple cooked apple, plum, thujonic, tobacco
Odor strength	high , recommend smelling in a 10.00 % solution or less
Substantivity	64 hour(s) at 100.00 %
Luebke, William tgsc, (2016)	At 10.00 % in dipropylene glycol. fruity floral rose green cooked apple plum thujonic tobacco
Flavor Type: Floral
floral, carrot, carrot seed, celery, watercress, thujonic
Luebke, William tgsc, (2016)	Floral carrot carrot seed celery watercress spicy thujonic

Potential Uses

Applications	fragrance agents
Odor purposes	Aldehydic , Citrus , Floral , Fruit , Herbal , Woody

Safety Information

Safety information


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 > 2000 mg/kg DAMSCONE GAMMA gives unique effects. Excellent results can be obtained with aldehydic, floral, woody, herbal, citrus and fruity notes.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Dermal sensitization
	View the IFRA Standard
View IFRA Standards Library for complete information.
Please review Amendment 49 IFRA documentation for complete information.
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%):
Category 1: Products applied to the lips
0.0077 %
Category 2: Products applied to the axillae
0.0023 %
Category 3: Products applied to the face/body using fingertips
0.046 %
Category 4: Products related to fine fragrance
0.043 %
	Category 5: Products applied to the face and body using the hands (palms), primarily leave-on
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on
0.011 %
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on
0.011 %
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on
0.011 %
Category 5D: Baby Creams, baby Oils and baby talc
0.011 %
Category 6: Products with oral and lip exposure
0.025 %
	Category 7: Products applied to the hair with some hand contact
Category 7A: Rinse-off products applied to the hair with some hand contact
0.088 %
Category 7B: Leave-on products applied to the hair with some hand contact
0.088 %
Category 8: Products with significant anogenital exposure
0.0045 %
Category 9: Products with body and hand exposure, primarily rinse off
0.084 %
	Category 10: Household care products with mostly hand contact
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products)
0.30 %
Category 10B: Household aerosol/spray products
0.30 %
	Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
0.17 %
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
0.17 %
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin
No Restriction
	Notes:
IFRA FLAVOR REQUIREMENTS:
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.
use level in formulae for use in cosmetics:
	0.0200 %
Dermal Systemic Exposure in Cosmetic Products:
	0.0005 mg/kg/day (IFRA, 2002)

Recommendation for gamma-damascone flavor usage levels up to:
	not for flavor use.