(R)-2-methyl butyric acid

General Material Information

Preferred name	(R)-2-methyl butyric acid
Trivial Name	(-)-2-Methylbutanoic acid
Short Description	butanoic acid, 2-methyl-, (R)-
Formula	C5 H10 O2
CAS Number	32231-50-8
FDA UNII	Search
Nikkaji Number	J57.315I
Bio Activity Summary	External link
NMR Predictor	External link
Synonyms	butanoic acid, 2-methyl-, (R)- (R)-2-methyl butanoic acid (2R)-2-methylbutanoic acid (R)-2-methylbutanoic acid (R)-2-methylbutyric acid Butanoic acid, 2-methyl-, (2R)- Butyric acid, 2-methyl-, (-)- (2R)-2-Methylbutanoic acid (R)-2-Methylbutanoic acid (R)-2-Methylbutyric acid (-)-2-Methylbutyric acid (R)-(-)-2-Methylbutanoic acid (-)-2-Methylbutanoic acid (-)-α-Methylbutyric acid (R)-(-)-2-Methylbutyric acid

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Literature & References

Leffingwell:	Chirality or Article
	(2R)-2-methylbutanoic acid
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	6950479
Pubchem (sid):	43558513

Publications by PubMed
Structural and Functional Analysis of the Loading Acyltransferase from Avermectin Modular Polyketide Synthase.
Biodegradation of C5-C 8 fatty acids and production of aroma volatiles by Myroides sp. ZB35 isolated from activated sludge.
Study on pharmacokinetics and tissue distribution of pteryxin in mice by ultra-pressure liquid chromatography with tandem mass spectrometry.
Pivalic acid acts as a starter unit in a fatty acid and antibiotic biosynthetic pathway in Alicyclobacillus, Rhodococcus and Streptomyces.
Stereoselective biocatalytic synthesis of (S)-2-hydroxy-2-methylbutyric acid via substrate engineering by using "thio-disguised" precursors and oxynitrilase catalysis.
Absolute configuration of the creatonotines and callimorphines, two classes of arctiid-specific pyrrolizidine alkaloids.
Requirements for the formation of a chiral template.
Chiral templating of surfaces: adsorption of (S)-2-methylbutanoic acid on Pt(111) single-crystal surfaces.
Asymmetric oxidation by Gluconobacter oxydans.
Enantiomers of cis-constrained and flexible 2-substituted GABA analogues exert opposite effects at recombinant GABA(C) receptors.
Stable isotope dilution analysis of wine fermentation products by HS-SPME-GC-MS.
2-ethylhydracrylic aciduria in short/branched-chain acyl-CoA dehydrogenase deficiency: application to diagnosis and implications for the R-pathway of isoleucine oxidation.
Role of alpha-methylacyl coenzyme A racemase in the degradation of methyl-branched alkanes by Mycobacterium sp. strain P101.
Total synthesis and biological evaluation of +-kalkitoxin, a cytotoxic metabolite of the cyanobacterium Lyngbya majuscula.
Enantioselective analysis of methyl-branched alcohols and acids in rhubarb (Rheum rhabarbarum L.) stalks.
Metabolism of ethyl tiglate in apple fruits leads to the formation of small amounts of (R)-ethyl 2-methylbutanoate.
Simultaneous enantioseparation of flobufen and its diastereomeric metabolites on ULMO, a Pirkle type chiral stationary phase.
Enantiomeric synthesis of (S)-2-methylbutanoic acid methyl ester, apple flavor, using lipases in organic solvent.
Components of the ether-insoluble resin glycoside-like fraction from Cuscuta chinensis.
Separation of the stereoisomers of the main metabolite of a non-steroidal anti-inflammatory drug, flobufen, by chiral high-performance liquid chromatography.
Branched-chain fatty acid requirement for avermectin production by a mutant of Streptomyces avermitilis lacking branched-chain 2-oxo acid dehydrogenase activity.
Stereoselectivity in the 2-methylbutyrate incorporation into anteiso fatty acids in Bacillus subtilis mutants.
Synthesis of stereoisomers of 8-methyl-2-decanol and esters attractive to severalDiabrotica sp.
Use of predator odors as repellents to reduce feeding damage by herbivores : I. Snowshoe hares (Lepus americanus).
Stereoselectivity of 1-aminocyclopropanecarboxylate malonyltransferase toward stereoisomers of 1-amino-2-ethylcyclopropanecarboxylic acid.
Studies of the glycine metabolism in a patient with D-glyceric acidemia and hyperglycinemia.
Demonstration of a new mammalian isoleucine catabolic pathway yielding an Rseries of metabolites.
Volatile fatty acid requirements of cellulolytic rumen bacteria.

Other Information

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
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HMDB (The Human Metabolome Database):	Search
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PhysChem Properties

Material listed in food chemical codex	No
Molecular weight	102.13310241699
Flash Point TCC Value	N/a
Solubility
water, 2.811e+004 mg/L @ 25 °C (est)	Yes

Organoleptic Properties

Odor Type: Cheesy
cheesy, sweaty
General comment	Cheesy sweaty

Safety Information

Safety information


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in use information

Category:
information only not used for fragrances or flavors
Recommendation for (R)-2-methyl butyric acid usage levels up to:
	not for fragrance use.

Recommendation for (R)-2-methyl butyric acid flavor usage levels up to:
	not for flavor use.

Safety references

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :6950479

National Institute of Allergy and Infectious Diseases:Data

(2R)-2-methylbutanoic acid